100 MHz~1 GHz家兔肺组织潮气量变化的介电特性研究

Dielectric properties of tidal volume changes in rabbit lung tissue in the 100 MHz~1 GHz band

本文针对在体条件下的肺组织介电特性随潮气量而发生变化展开研究,为微波成像等技术提供可靠有效的先验信息。本研究在100 MHz~1 GHz频段采用开端同轴探头法,对30只家兔肺组织的介电特性进行在体测量,设置6组不同的潮气量(30、40、50、60、70、80 mL)研究其介电特性变化趋势,并且对2个特定频率点(433、915 MHz)的数据进行统计学分析。结果发现,在100 MHz~1 GHz频率范围内,随着潮气量增大,肺组织的介电系数和电导率均呈现下降的趋势,在2个特定频率点和6组潮气量下,肺组织介电特性差异具有统计学意义。本文研究表明,肺组织的介电特性随潮气量增大呈非线性变化趋势。以此为依据,本文可为微波成像等生物电磁成像技术提供更精确的生物组织介电特性参数,为改进肺部疾病诊断方法和设备提供了科学依据和实验数据支持。

This paper investigates the variation of lung tissue dielectric properties with tidal volume under in vivo conditions to provide reliable and valid a priori information for techniques such as microwave imaging.In this study,the dielectric properties of the lung tissue of 30 rabbits were measured in vivo using the open-end coaxial probe method in the frequency band of 100 MHz to 1 GHz,and 6 different sets of tidal volumes(30,40,50,60,70,80 mL)were set up to study the trends of the dielectric properties,and the data at 2 specific frequency points(433 and 915 MHz)were analyzed statistically.It was found that the dielectric coefficient and conductivity of lung tissue tended to decrease with increasing tidal volume in the frequency range of 100 MHz to 1 GHz,and the differences in the dielectric properties of lung tissue for the 6 groups of tidal volumes at 2 specific frequency points were statistically significant.This paper showed that the dielectric properties of lung tissue tend to vary non-linearly with increasing tidal volume.Based on this,more accurate biological tissue parameters can be provided for bioelectromagnetic imaging techniques such as microwave imaging,which could provide a scientific basis and experimental data support for the improvement of diagnostic methods and equipment forlung diseases.