摘要
In a recent study published in Cell,Tieu et al.used RfxCas13d to dynamically enhance performance and longevity of chimeric antigen receptor(CAR)T cells by massively multiplexed gene knockdown and thereby,move the treatment one step closer towards“off-the-shelf”next-generation medicine.
基金
This work was supported by the Bundesministerium für Bildung und Forschung(BMBF,Federal Ministry of Education and Research)under grant number 13GW0493(MERGE)
C.D.gratefully acknowledges the OrChESTRA project from the European Union’s Horizon Europe’s research and innovation program under Grant Agreement No.101079473.
