积雪草研究热点及趋势可视化分析

Visualization Analysis of Research Hotspot and Trend in Jixuecao(Centellae Herba)

目标:对积雪草的相关研究进行文献计量学和可视化分析,总结该研究领域的研究进展、研究热点及趋势。方法:检索中国知网(CNKI)、万方数据、维普数据库(VIP)、中国生物医学文献数据库(CBM)2000年1月1日至2023年11月15日收录的积雪草相关研究文献。利用NoteExpress 3.9软件整理文献题录,通过CiteSpace 6.2.R5软件对作者、研究机构及关键词进行可视化分析。结果:纳入829篇文献,年发文量整体呈波动上升趋势;来源期刊324种,载文量最多的是《中国中西医结合肾病杂志》(26篇);涉及696位作者,发文量最多的是朱晓玲(24篇),核心作者包括朱晓玲、王永钧、章卓等;核心研究机构有海军军医大学、浙江中医药大学第一附属医院、重庆医科大学等;高频关键词有“积雪草苷”“积雪草酸”“中药复方”等。结论:积雪草当前的研究热点主要集中在化学成分、生物效应、研究方法和疾病治疗4个方面。积雪草酸及其抗炎、抗氧化、增殖、凋亡、抗肿瘤等领域是未来积雪草研究的重点趋势。

Objective:To conduct bibliometric and visual analysis on the relevant research of Jixuecao(Centellae Herba),and summarize the research progress,hotspots,and trends in this field.Methods:The literatures related to Jixuecao(Centellae Herba)were retrieved from China National Knowledge Infrastructure(CNKI),Wanfang Data,VIP Database(VIP),and China Biomedical Literature Database(CBM)from January 1,2000 to November 15,2023.NoteExpress3.9 software was used to organize the bibliothems,and CiteSpace 6.2.R5 software was used to visualize the authors,research institutions and keywords.Results:A total of 829 papers were included,with an overall fluctuating upward trend in the number of annual publications.The source journals were 324,and the journal with the highest number of articles was Chinese Journal of Integrated Traditional and Western Nephrology(26 articles).696 authors were involved,ZHU Xiaoling has the highest number of articles(24 articles),and the core authors included ZHU Xiaolin,WANG Yongjun,ZHANG Zhuo,etc.The core research institutions included Naval Medical University,The First Affiliated Hospital of Zhejiang University of Traditional Chinese Medicine,Chongqing Medical University,etc.High-frequency keywords included"Centella asiatica glycoside","Centella asiatica acid","Chinese medicine compound"and so on.Conclusion:The current research hotspots in Jixuecao(Centellae Herba)are chemical composition,biological effects,research methods and disease treatment and so on.The key research trend in this field is asiatic acid,antioxidant,proliferation,apoptosis and anti-tumor.Conclusion:The current research hotspots of Jixuecao(Centellae Herba)mainly focus on four aspects:chemical composition,biological effects,research methods,and disease treatment.Centella asiatica acid and its anti-inflammatory,antioxidant,proliferative,apoptotic,anti-tumor and other fields are the key trends in future research on Jixuecao(Centellae Herba).