针刺治疗Ⅱ型糖尿病效应机制研究进展

Research progress on the mechanism of acupuncture on typeⅡdiabetes mellitus

针刺是治疗二型糖尿病(T2DM)的有效措施,大量研究表明针刺能改善T2DM,但其作用机制尚未充分阐明。本文对针刺治疗T2DM的机制研究进行梳理,总结出针刺治疗T2DM的效应机制与改善胰岛素抵抗、调节炎性反应、促进胰岛素分泌、改善脂质代谢紊乱、抵抗氧化应激损伤、改善肥胖、调节肠道菌群、调节神经系统等密切相关,同时也指出目前相关研究的不足和未来研究的方向,为进一步探索针刺降糖的作用机制提供参考。

Acupuncture is an effective measure for treating type 2 diabetes mellitus(T2DM).Many studies have shown that acupuncture can reduce blood glucose in patients with T2DM,but its mechanism is still unclear.This review summarized the mechanism of acupuncture on T2DM,the mechanisms of acupuncture in treating T2DM is related to improving insulin resistance,regulating inflammation,promoting insulin secretion,improving lipid metabolism disorders,resisting oxidative stress,improving obesity,controlling intestinal flora,and regulating the nervous system.At the same time,this review also points out the lack of current relevant research and the future research directions to provide a reference for further exploring the mechanism of acupuncture hypoglycemic action.