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卡前列素氨丁三醇联合子宫填塞球囊对剖宫产难治性产后出血的止血效果

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摘要 目的 探讨卡前列素氨丁三醇联合子宫球囊填塞在剖宫产难治性产后出血治疗中的有效性及安全性。方法选择2018年1月至2023年10月江西省赣州市于都县第二人民医院收治的62例剖宫产难治性产后出血患者,均深部肌内注射卡前列素氨丁三醇,根据药物联合外科止血方法的不同,分组为对照组30例与联合组32例。对照组联合宫腔纱布填塞术治疗,联合组联合子宫球囊填塞术治疗,记录并对比两组患者出血和输血情况、术后恢复情况以及凝血功能指标[凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、血清纤维蛋白原水平(FIB)],统计不良反应发生情况。结果 与对照组对比,联合组术后2、24 h出血量和输注全血量明显减少,术后24 h血红蛋白水平明显升高,住院时间、恶露持续时间均明显缩短;两组术后24 h PT、APTT、FIB水平对比,联合组低于对照组,差异有统计学意义(P<0.05)。两组不良反应发生率对比,差异无统计学意义(P>0.05)。结论 在剖宫产难治性产后出血的治疗中,应用卡前列素氨丁三醇联合子宫球囊填塞方案可实现有效止血,在降低剖宫产产妇出血量、恢复产妇凝血功能方面更具优势,且安全性好。
出处 《实用中西医结合临床》 2024年第7期75-78,共4页 Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine
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