中医传统功法在卒中后认知障碍患者中应用效果的Meta分析

Meta-analysis of the application effect of Traditional Chinese Medicine exercises in patients with post-stroke cognitive impairment

目的系统评价中医传统功法对卒中后认知障碍患者的干预效果。方法利用计算机检索The Cochrane Library、PubMed、Embase、Web of Science、中国生物医学文献数据库、中国知网、万方数据知识服务平台、维普中文科技期刊数据库中有关中医传统功法干预卒中后认知障碍患者的随机对照试验,检索时限为建库至2023年12月31日,采用RevMan 5.4软件进行Meta分析。结果共纳入15项随机对照试验研究,包括918例研究对象。Meta分析结果显示,中医传统功法在提高卒中后认知障碍患者的认知功能[SMD=0.86,95%CI(0.68,1.04),P<0.001]、缩短P300检测的潜伏时间[MD=-11.52,95%CI(-16.06,-6.98),P<0.001]、增加P300检测的波幅高度[MD=1.06,95%CI(0.44,1.67),P<0.001]等方面均优于对照组。结论中医传统功法可有效提高卒中后认知障碍患者的认知功能。

Objective To systematically evaluate the intervention effect of Traditional Chinese Medicine on patients with post-stroke cognitive impairment.Methods The Cochrane Library,PubMed,Embase,Web of Science,Chinese Biomedical Literature Database,CNKI,Wanfang Data Knowledge Service Platform,and VIP Chinese Science and Technology Journal Database were searched by computer for randomized controlled trials of Traditional Chinese Medicine exercises on patients with post-stroke cognitive impairment.The search time was from the establishment of the database to December 31,2023.Meta-analysis was performed using RevMan 5.4 software.Results A total of 15 randomized controlled trials were included,including 918 subjects.The results of Meta-analysis showed that the Traditional Chinese Medicine exercises were superior to the control group in improving the cognitive function of patients with post-stroke cognitive impairment[SMD=0.86,95%CI(0.68,1.04),P<0.001],shortening the latency time of P300 detection[MD=-11.52,95%CI(-16.06,-6.98),P<0.001],and increasing the amplitude height of P300 detection[MD=1.06,95%CI(0.44,1.67),P<0.001].Conclusion Traditional Chinese Medicine exercises can effectively improve the cognitive function of post-stroke cognitive impairment patients.