仝小林运用“有毒”中药治疗代谢性疾病经验

TONG Xiaolin's Experience in Using"Poisonous"Chinese Material Medica to Treat Metabolic Diseases

总结仝小林运用“有毒”中药治疗代谢性疾病的临证经验,认为可通过斟酌剂量、合理配伍、炮制煎服等方法以达到减毒增效的目的。结合中药功效和现代药理、毒理学,总结黄连治疗糖尿病,细辛、大黄、水蛭治疗糖尿病肾脏疾病,制川乌、制草乌、细辛、制马钱子治疗糖尿病周围神经病变,淫羊藿、蜈蚣治疗糖尿病性勃起功能障碍,附子、半夏治疗糖尿病胃轻瘫,红曲、威灵仙治疗代谢性综合征,雷公藤、黄药子治疗甲状腺功能亢进症的临证剂量特色、配伍用药、煎服法及其他注意事项,为临床精准用药提供参考。

This paper summarized TONG Xiaolin's clinical experience in using"poisonous"Chinese material medica to treat metabolic diseases,who believes that toxicity reducing and efficacy enhancing can be achieved through carefully considered dosage,reasonable combination of medicinals,and appropriate preparation and administration ways.By analyzing the functions of Chinese material medica and findings from modern pharmacology and toxicology,the clinical dosage features,combination of medicinals and medication,preparation and administration methods and other precautions have been summarized regarding Huanglian(Rhizoma Coptidis)in treating diabetes,Xixin(Radix et Rhizoma Asari),Dahuang(Radix et Rhizoma Rhei)and Shuizhi(Hirudo)in treating diabetic kidney diseases,Zhichuanwu(Radix Aconiti Praeparata),Zhicaowu(Radix Aconiti Kusnezoffii Praeparata),Xixin and Zhimaqianzi(Semen Strychni Praeparata)in treating diabetic peripheral neuropathy,Yinyanghuo(Herba Epimedii)and Wugong(Scolopendra)in treating diabetic erectile dysfunction,Fuzi(Radix Aconiti Lateralis Praeparata)and Banxia(Rhizoma Pinelliae)in treating diabetic gastroparesis,Hongqu(Monascus purpureus Went)and Weilingxian(Radix et Rhizoma Clematidis)in treating metabolic syndrome,as well as Leigongteng(Radix Tripterygii Wilfordii)and Huangyaozi(Rhizoma Dioscoreae Bulbiferae)in treating Hyperthyroidism,thereby providing reference for precise clinical medication.