超分子水杨酸联合强脉冲光对中重度痤疮的治疗作用研究

Treatment Effect of Supramolecular Salicylic Acid Combined with Intense Pulse Light on Moderate to Severe Acne

目的 分析在中重度痤疮治疗中超分子水杨酸联合强脉冲光的应用价值。方法 将某院近年来收治的中重度痤疮患者共60例作为本次观察对象,以随机法(数字表法)分组,观察组30例采取超分子水杨酸联合强脉冲光治疗,对照组30例采取超分子水杨酸治疗,比较两组临床疗效及治疗前后红斑评估量表(CEA)、躯干痤疮严重程度量表(TRASS)评分,皮损计数(粉刺、炎性丘疹、脓疱、囊肿、结节)。结果 治疗4次后,观察组临床疗效高于对照组(P<0.05);观察组CEA、TRASS评分、皮损计数较对照组改善更明显(P均<0.05)。结论 在中重度痤疮治疗中采取超分子水杨酸联合强脉冲光治疗可提高治疗效果,减轻痤疮严重程度,较单独用超分子水杨酸治疗更能减少皮损计数,减轻红斑症状,有助于促进治疗后康复。

Objective To analyze the application value of supramolecular salicylic acid combined with intense pulse light treatment in the treatment of moderate to severe acne.Methods A total of 60 cases of moderate-to-severe acne patients admitted to a hospital in recent years were used as the subjects of this observation,grouped by randomization method(digital table method),30 cases in the observation group were treated with supramolecular salicylic acid combined with intense pulsed light,and 30 cases in the control group were treated with supramolecular salicylic acid,and the clinical efficacy of the two groups was compared.Compare the clinical efficacy of the two groups and the scores of Erythema Evaluation Scale(CEA) and Trunk Acne Severity Scale(TRASS) before and after treatment,and the count of skin lesions(acne,inflammatory papules,pustules,cysts,nodules).Results After 4 treatments,the clinical efficacy of the observation group was higher than that of the control group(P<0.05);the CEA,TRASS score,and lesion count of the observation group improved more significantly than that of the control group(all P<0.05).Conclusion The use of supramolecular salicylic acid in combination with intense pulsed light in the treatment of moderate to severe acne improves the treatment effect,reduces the severity of acne,reduces lesion counts and erythema symptoms more than supramolecular salicylic acid alone,and helps to promote healing after treatment.