魏玮基于“脑肠同调”治疗胃食管反流病经验

WEI Wei's experience in treatment of gastroesophageal reflux disease based on“Brain-gut Coregulation”

胃食管反流病是以脑肠互动异常为特征的消化系统难治性疾病。其发病机制为肝胆疏泄之枢(情志-脑)、脾胃升降之枢(消化-肠)失调,临床表现有反酸、烧心等消化系统(肠)症状,和焦虑、抑郁等精神心理(脑)症状。魏玮教授创新提出“脑肠同调”理论,并结合本病发病机制及临床表现,灵活运用辛开苦降调枢、疏肝解郁调枢、敛阳安神调枢法及情志疗法,同步改善“脑”“肠”症状,以达脑肠同调共治目的。

Gastroesophageal reflux disease is a refractory disease of the digestive system characterized by abnormal brain-gut interaction.Impaired dispersion of the liver and gallbladder(emotion-brain)and abnormal rise and fall of the spleen and stomach(digestion-intestine)are its pathogenesis.Clinical manifestations include acid reflux,heartburn(gut),anxiety and depression(brain).Taking into account comprehensively,Professor Wei Wei innovatively proposed the theory of"Brain-gut Coregulation",and flexibly used different treatment methods to simultaneously improve the symptoms of"brain"and"gut",so as to Achieve the purpose of harmony.This paper discusses the theoretical connotation,pathophysiological mechanism and clinical application experience of"Brain-gut Co-regulation",hoping to provide a reference for the treatment of gastroesophageal reflux disease.