恶性肺磨玻璃结节的独立危险因素分析

Analysis of Independent Risk Factors for Malignant Pulmonary Glass Nodule

目的:分析恶性肺磨玻璃结节的独立危险因素。方法:回顾性分析2022年1月—2023年12月马鞍山市和县人民医院收治的肺磨玻璃结节患者79例的病历资料,根据病理结果分为良性组(n=37)和恶性组(n=42)。比较两组患者临床资料,采用Logistic二元回归分析恶性肺磨玻璃结节的独立危险因素。结果:两组性别、年龄、血管集束征情况比较,差异无统计学意义(P>0.05);恶性组有吸烟史、结节直径≥1 cm、混合密度磨玻璃结节、有毛刺征占比高于良性组,差异有统计学意义(P<0.05)。Logistic二元回归分析结果显示,有吸烟史、结节直径≥1 cm、混合密度磨玻璃结节、有毛刺征为恶性肺磨玻璃结节的独立危险因素(P<0.05)。结论:有吸烟史、结节直径≥1 cm、混合密度磨玻璃结节、有毛刺征为恶性肺磨玻璃结节的独立危险因素,临床可根据这些特征预测患者病情。

Objective:To analyze the independent risk factors of malignant pulmonary glass nodule.Methods:The medical records of 79 patients with pulmonary grinding glass nodules were retrospectively analyzed at the He County People's Hospital of Maanshan City from January 2022 to December 2023.According to pathological findings,they were divided into benign group(n=37)and malignant group(n=42).The clinical data of the two groups were compared,and the independent risk factors of malignant pulmonary grinding glass nodules were analyzed by Logistic binary regression.Results:There was no significant difference in gender,age and vascular cluster signs between the two groups(P>0.05).The proportion of smoking history,nodule diameter≥1 cm,mixed density glass nodule and burr in malignant group was higher than that in benign group,and the difference was statistically significant(P<0.05).Logistic binary regression analysis showed that smoking history,nodule diameter≥1 cm,mixed density glass nodule and burr sign were independent risk factors for malignant pulmonary glass nodule(P<0.05).Conclusion:Smoking history,nodule diameter≥1 cm,mixed density glass nodule and burr sign are independent risk factors for malignant lung glass nodule,which can be used to predict patients'disease.