老年人共病和肌少症的研究进展

Recent Advances in Understanding Multimorbidity and Sarcopenia in the Elderly

由于器官功能的退化及疾病易感性的增加,多病共存的现象在老年人群中普遍存在。肌少症是一种进行性和全身性骨骼肌疾病,与很多慢性疾病有共同的危险因素。共病和肌少症都是老年人常见问题,两者相互影响,共同导致老年人衰弱、失能和其他不良事件,影响老年人的生活质量。现有的研究大多是单一疾病和肌少症之间的关系,对于共病和肌少症之间的研究较少。本文对共病和肌少症之间的关系进行综述,以找出该领域信息的局限性,并提出未来研究的可能方向。

The aged often have multimorbidity,which arises from the decline in organ functioning and heightened vulnerability to illnesses.Sarcopenia,an advancing and widespread skeletal muscle illness,has common risk factors with many chronic disorders that are common among this population.The simultaneous presence of many chronic conditions and age-related loss of muscle mass and strength,known as multimorbidity and sarcopenia respectively,often worsens physical weakness and functional impairment in older individuals,significantly compromising their overall well-being.While most current studies primarily focus on the connection between individual illnesses and sarcopenia,there is a lack of research that investigates the relationship between several health conditions and sarcopenia.This review examines the existing comprehension of the interaction between multimorbidity and sarcopenia,with the goal of identifying areas of limited information and proposing potential avenues for future research.