高血压患者发生心血管疾病的危险因素分析

Analysis of Risk Factors of Cardiovascular Disease in Hypertensive Patients

目的:分析高血压患者发生心血管疾病的影响因素。方法:回顾性分析广东省茂名农垦医院2021年1月—2022年12月收治的80例高血压患者的临床资料,按照发生及未发生心血管疾病分为发生组和未发生组,各40例。分析两组临床资料,筛选高血压患者发生心血管疾病的影响因素。结果:发生组和未发生组年龄、性别、高血压病程、收缩压、舒张压、脂联素、血红蛋白水平比较,差异无统计学意义(P>0.05);发生组超敏C反应蛋白(hs-CRP)、同型半胱氨酸(Hcy)水平高于未发生组,二磷酸腺苷(ADP)水平低于未发生组,差异有统计学意义(P<0.001)。Logistic回归分析结果显示,hs-CRP、Hcy是高血压患者发生心血管疾病的独立危险因素,ADP是高血压患者发生心血管疾病的独立保护因素(P<0.05)。结论:hs-CRP、Hcy是高血压患者发生心血管疾病的独立危险因素,ADP是高血压患者发生心血管疾病的独立保护因素。

Objective:To analyze the influencing factors of cardiovascular disease in hypertensive patients.Methods:Clinical data of eighty patients with hypertension admitted to Guangdong Maoming Nongken Hospital from January 2021 to December 2022 were retrospectively analyzed.According to the occurrence and non-occurrence of cardiovascular disease,they were divided into occurrence group and non-occurrence group,with forty cases each.The clinical data of the two groups was analyzed to screen the influencing factors of cardiovascular disease in hypertensive patients.Results:There was no significant difference in age,gender,course of hypertension,systolic blood pressure,diastolic blood pressure,adiponectin and hemoglobin levels between the occurrence group and non-occurrence group(P>0.05);the levels of hypersensitive C-reactive protein(hs-CRP)and homocysteine(Hcy)in the occurrence group were higher than those in the non-occurrence group,and the levels of adenosine diphosphate(ADP)were lower than those in the non-occurrence group,the difference was statistically significant(P<0.001).Logistic regression analysis showed that hs-CRP and Hcy were independent risk factors for cardiovascular disease in hypertensive patients,and ADP was independent protective factor for cardiovascular disease in hypertensive patients(P<0.05).Conclusion:hs-CRP and Hcy are independent risk factors for cardiovascular disease in hypertensive patients,and ADP is independent protective factor for cardiovascular disease in hypertensive patients.