康复新液治疗慢性糜烂性胃炎的临床效果

Clinical Effect of Kangfuxin Fluid on Chronic Erosive Gastritis

目的:分析康复新液治疗慢性糜烂性胃炎的临床效果。方法:选取2018年10月—2022年12月遵义市习水县人民医院消化内科收治的慢性糜烂性胃炎患者120例作为研究对象,采取电脑随机分组方式分为对照组和观察组,各60例。对照组采用兰索拉唑联合铝碳酸镁咀嚼片治疗,观察组在对照组基础上采用康复新液治疗。比较两组治疗效果、症状评分、幽门螺杆菌根除率、胃泌素水平。结果:观察组治疗总有效率高于对照组,差异有统计学意义(P=0.015)。治疗前,两组胃胀、嗳气、胃痛、纳差评分比较,差异无统计学意义(P>0.05);治疗后,两组胃胀、嗳气、胃痛、纳差评分低于治疗前,观察组低于对照组,差异有统计学意义(P<0.05)。观察组幽门螺杆菌根除率高于对照组,差异有统计学意义(P=0.024)。治疗前,两组胃泌素水平比较,差异无统计学意义(P>0.05);治疗后,两组胃泌素水平低于治疗前,观察组低于对照组,差异有统计学意义(P<0.05)。结论:在兰索拉唑、铝碳酸镁咀嚼片基础上给予康复新液治疗糜烂性胃炎的效果显著,能有效改善临床症状,提高幽门螺杆菌根除率,降低胃泌素水平。

Objective:To analyze the clinical effect of Kangfuxin fluid on chronic erosive gastritis.Methods:A total of one hundred and twenty patients with chronic erosive gastritis admitted to the Department of Gastroenterology,Zunyi Xishui County People's Hospital from October 2018 to December 2022 were selected as the study objects,and were divided into control group and observation group by computer randomized method,with sixty cases in each group.The control group was treated with lansoprazole combined with aluminum magnesium carbonate chewable tablets,and the observation group was treated with Kangfuxin fluid on the basis of the control group.The therapeutic effect,symptom score,Helicobacter pylori eradication rate and gastrin level were compared between the two groups.Results:The total effective rate of the observation group was higher than that of the control group,the difference was statistically significant(P=0.015).Before treatment,there was no significant difference in the scores of distension,belching,stomachache and poor appetite between the two groups(P>0.05);after treatment,the scores of gastric distension,belching,stomachache and poor appetite in the two groups were lower than before treatment,and the observation group was lower than the control group,with statistical significance(P<0.05).The eradication rate of Helicobacter pylori in observation group was higher than that in control group,and the difference was statistically significant(P=0.024).Before treatment,there was no significant difference in gastrin level between the two groups(P>0.05);after treatment,the gastrin level in the two groups was lower than before treatment,and the observation group was lower than the control group,with statistical significance(P<0.05).Conclusion:Kangfuxin fluid on the basis of lansopzole and aluminum magnesium carbonate chewable tablets can effectively improve the clinical symptoms,increase the eradication rate of Helicobacter pylori and reduce the level of gastrin in the treatment of erosive gastritis.