预后营养指数与急性ST段抬高型心肌梗死患者发生复杂室性心律失常的相关性分析

Correlation Analysis between Prognostic Nutritional Index and Complex Ventricular Arrhythmiasin Patients with Acute ST Segment Elevation Myocardial Infarction

目的:探讨预后营养指数(PNI)与急性ST段抬高型心肌梗死(STEMI)患者发生复杂室性心律失常(CVA)的关系。方法:选取急性STEMI患者301例,根据是否发生CVA分为CVA组(n=85)和非CVA组(n=216)。比较2组一般情况和实验室指标,利用Logistic回归分析PNI与急性STEMI患者发生CVA的关系。结果:2组年龄、性别、BMI、高血压病史、糖尿病病史、吸烟史差异无统计学意义(P>0.05);CVA组血清白蛋白、PNI、血钾、左心室射血分数(LVEF)显著低于非CVA组,C反应蛋白、Gensini评分、Killip分级≥Ⅱ级、受累室壁为前壁显著高于非CVA组,差异有统计学意义(P <0.05);多因素Logistic回归分析显示,PNI(OR=0.469)与急性STEMI患者发生CVA有关,其他危险因素还有低LVEF、低血钾、CRP升高。结论:PNI是急性STEMI患者发生CVA的危险因素,可作为临床预测急性STEMI患者发生CVA的辅助指标。

Objective:To explore the relationship between prognostic nutritional index(PNI)and the occurrence of complex ventricular arrhythmias(CVA)in patients with acute ST segment elevation myocardial infarction(STEMI).Methods:A retrospective selection was conducted on 301 patients with acute STEMI,who were divided into a CVA group(n=85)and a non-CVA group(n=216)based on the occurrence of CVA.The general data and laboratory indexes of the two groups were compared,and logistic regression was used to analyze the relationship between PNI and the occurrence of CVA in acute STEMI patients.Results:There was no significant difference in age,sex,BMI,hypertension history,diabetes history and smoking history between the two groups(P>0.05).The comparison of laboratory indicators showed that serum albumin,PNI,blood potassium,and LVEF in the CVA group were significantly lower than those in the non-CVA group.C-reactive protein,Gensini score,Killip grade≥Ⅱ,and anterior wall involvement were significantly higher than those in the non-CVA group(P<0.05).Multivariate logistic regression analysis showed that PNI(OR=0.469)was associated with CVA in acute STEMI patients,while other risk factors included LVEF,blood potassium and CRP.Conclusion:PNI is a risk factor for the CVA in acute STEMI patients and can serve as an auxiliary indicator for clinical prediction of CVA in acute STEMI patients.