摘要
人工心脏(血泵)应兼具优良的水力学性能和血液相容性,血泵性能的提升依赖于良好的优化设计方法。本文对近年离心式血泵优化设计相关的工作进行总结,首先回顾数值模拟方法的进展,高保真度的流场数值模拟是进行血泵优化设计的先决条件;接着主要从叶轮、蜗壳、间隙等方面概括优化设计的参数敏感性研究;总结优化设计常用的几种方法,包括参数敏感性研究、正交优化、机器学习/遗传算法、拓扑优化;最后提出血泵优化设计的展望及存在的挑战。研究结果可为未来的血泵优化设计工作提供有益的借鉴和参考。
Artificial hearts(blood pumps)exhibit excellent hydraulic performance and compatibility with blood.Improvement in blood pump performance depends on the design and optimization method.This review summarizes relevant work on designing and optimizing centrifugal blood pumps.First,the progress of numerical simulation methods is reviewed.High-fidelity flow field numerical simulations are prerequisites for design and optimization.The parameter sensitivity studies are summarized mainly from the aspects of the impeller,volute,and clearances.Several commonly used design and optimization methods have been summarized,including parameter sensitivity research,orthogonal optimization,machine learning/genetic algorithms,and topology optimization.Finally,the prospects and challenges for designing and optimizing blood pumps are discussed.This review provides valuable references and guidance for the future design and optimization of blood pumps.
作者
张珂嘉
吴鹏
ZHANG Kejia;WU Peng(Artificial Organ Technology Laboratory,School of Mechanical and Electrical Engineering,Soochow University,Suzhou 215131,Jiangsu,China;Jiangsu Key Laboratory for Design and Manufacture of Micro-Nano Biomedical Instruments,School of Mechanical Engineering,Southeast University,Nanjing 211189,China)
出处
《医用生物力学》
CAS
CSCD
北大核心
2024年第3期552-558,共7页
Journal of Medical Biomechanics
基金
国家自然科学基金项目(12072216)
国家自然科学基金中德合作与交流项目(M-0231)。
关键词
血泵
叶轮
蜗壳
优化设计
数值模拟
blood pump
impeller
volute
design and optimization
numerical simulation
