分子印迹聚合物在真菌毒素检测中的研究进展

Recent Advances of Molecularly Imprinted Polymers in Mycotoxin Detection

真菌毒素污染严重威胁食品安全和生命健康,建立灵敏、快速的真菌毒素检测方法至关重要。分子印迹聚合物(MIPs)具有构效预定性、特异识别性和广泛适用性的优点;作为亲缘分离介质,既可用于样品前处理,亦可充当识别元件用于传感分析,在真菌毒素检测领域极具应用潜力。首先介绍了MIPs的基本原理和合成方法,然后结合近年来食品和农产品中真菌毒素检测实例综述了MIPs在样品前处理、光学传感、电化学传感、压电传感等领域的应用研究进展,最后总结该领域存在的挑战并展望潜在发展方向,以期为MIPs在真菌毒素检测领域的研究提供参考。

Mycotoxin contaminations bring serious threats to food safety and human health,hence it is important to establish the sensitive and rapid methods for mycotoxin detection.Molecularly imprinted polymers(MIPs)possess the advantages of pre-determined structure,specific recognition,and applicability,which endow it with great potential in mycotoxin detection.As the selective separation medium,MIPs can be used for sample pretreatment and sensing analysis.This review outlined the basic principle and synthetic methods of MIPs,followed by the discussion on recent advances in the application of MIPs toward sample pretreatment,optical sensing,electrochemical sensing,and piezoelectric sensing.Moreover,the challenges and future directions in the application of MIPs in mycotoxin detection are also discussed,providing insights for further research and development in this area.