一种新型超声显影导管声学特性研究

Acoustic performance of a newly knitted catheter with an improved ultrasonography visibility

目的探讨新型编织导管的超声显影能力。方法使用电子显微镜观察、水听器声波信号检测、水槽导管环成像实验和活体猪肝脏实验,对比普通塑胶导管(n=10)与自制新型编织导管(n=10)在管壁结构、反射声波信号强度及在液体和活体动物肝脏组织超声显影能力方面的差异。结果电镜下,新型编织导管管壁内可见与管体声阻抗不同的交叉成网的高分子材料纤维丝,纤维丝交叉点周围存在微气泡;水听器声波信号检测实验显示新型编织导管反射后接收到的基波和二次谐波信号分布更为均匀,角度依赖性小;在水槽导管环成像实验,新型编织导管管壁完整显示率为(91.9±1.2)%,管壁回声失落率为(4.0±0.7)%,多重反射伪像显示率为(4.3±0.9)%,均与普通塑胶导管存在显著性差异(P<0.01);活体猪肝脏实验显示新型编织导管超声回声强度、管壁连续性和尖端显影均优于普通塑胶导管。结论新型编织导管具有更强的超声显影能力,可能具有较好的临床应用前景。

Objective This study was conducted to investigate ultrasonography visibility of a newly knitted catheter.Methods Tube wall structure,reflected acoustic signal intensity and ultrasonography visibility in liquid and living animal liver tissue between conventional plastic catheter(n=10)and newly knitted catheter(n=10)were compared by through electron microscopy,hydrophone acoustic signal detection,flume catheter ring experiment and live pig liver implantation.Results Under electron microscope,interlaced polymer fibers were observed in the wall of the newly knitted tube,whose acoustic impedance values were different from those of the tube body,and microbubbles were also observed around the intersections of fibers;hydrophone detection experiments showed that the fundamental and second harmonic signals received by the newly knitted catheter were more evenly distributed and less angle dependent;in the catheter ring experiment,complete display rate was(91.9±1.2)%,echo loss rate was(4.0±0.7)% and multiple reflection artifact display rate was(4.3±0.9)%,all much superior to conventional plastic catheter(P<0.01);in live pig liver in vivo,the echo intensity,wall continuity and tip development of the newly knitted catheter were much better than those of conventional plastic catheter.Conclusion The newly knitted catheter has stronger ultrasound visibility,which might be validated in clinical application.