复方维生素饮品对小鼠体力疲劳的缓解作用研究

Relieving Effect Study of Compound Vitamin Drinks on Physical Fatigue in Mice

目的:探究复方维生素饮品对缓解体力疲劳的作用。方法:实验设置了3个不同剂量复方维生素饮品组别,分别为人体推荐剂量的5倍、10倍和30倍,连续对小鼠灌胃32 d。实验结束后,对小鼠疲劳的相关指标进行综合评估。结果:与空白对照组相比,复方维生素饮品各剂量组小鼠负重游泳时间延长,体内肌糖原、肝糖原含量增加,血尿素含量下降,且血乳酸曲线下面积减小,肌酸激酶活力减弱,乳酸脱氢酶活力增强,差异均具有统计学意义(P<0.05,P<0.01)。结论:复方维生素饮品可通过提高机体运动耐力,维持能量代谢平衡,抑制并清除运动生成和积累的代谢产物以及调解相关酶活力,达到缓解体力疲劳的作用。

Objective:Explore the effect of compound vitamin drinks on relieving physical fatigue.Method:Three groups of compound vitamin drinks with different doses were set up in the experiment,which were 5 times,10 times,and 30 times the recommended dose for the human body,and mice were continuously gavaged for 32 days.After the experiment,a comprehensive evaluation of the relevant indicators of fatigue in mice was conducted.Result:Compared with the blank control group,the weight bearing swimming time of mice in each dose group of compound vitamin drink was prolonged,the content of muscle glycogen and liver glycogen increased,the content of blood urea decreased,and the area under the blood lactate curve decreased,creatine kinase activity weakened,and lactate dehydrogenase activity increased,the differences are statistically significant(P<0.05,P<0.01).Conclusion:Compound vitamin drinks can alleviate physical fatigue by improving physical endurance,maintaining energy metabolism balance,inhibiting and clearing metabolic products generated and accumulated during exercise,and regulating related enzyme activity.