柳叶蜡梅精油纳米乳液的制备及其性质研究

Study on preparation and properties of Chimonanthus salicifolius essential oil nano-emulsion

采用超声乳化法制备柳叶蜡梅精油纳米乳液。通过单因素试验确定柳叶蜡梅精油纳米乳液的最佳制备工艺条件,并进行稳定性、抑菌性和抗氧化活性分析。结果表明:最佳工艺条件为以纳米乳液质量为基准,柳叶蜡梅精油添加量5%、表面活性剂(Span20)添加量4%、助表面活性剂(无水乙醇)添加量1%、超纯水添加量90%。在此条件下制备得到的柳叶蜡梅精油纳米乳液的平均粒径为(117.80±0.16)nm,分散指数(PDI)为0.17±0.01,Zeta电位为(-45.03±0.46)mV。制备的柳叶蜡梅精油纳米乳液具有良好的稳定性、抑菌性和抗氧化活性。

Chimonanthus salicifolius essential oil nano-emulsion was prepared by ultrasonic emulsification.The optimum preparation conditions of Chimonanthus salicifolius essential oil nano-emulsion were determined by single factor experiments,and the stability,antibacterial and antioxidant activity were analyzed.The results showed that the optimum process conditions were based on the mass of nano-emulsion,Chimonanthus salicifolius essential oil addition amount 5%,surfactant(Span20)addition amount 4%,cosurfactant(anhydrous ethanol)addition amount 1%,and ultra-pure water addition amount 90%.Under these conditions,the average particle size of Chimonanthus salicifolius essential oil nano-emulsion was(117.80±0.16)nm,the dispersion index(PDI)was 0.17±0.01,and the Zeta potential was(-45.03±0.46)mV.The prepared Chimonanthus salicifolius essential oil nano-emulsion had good stability,antibacterial and antioxidant activity.