单分子光谱在化学领域的应用进展与展望

Review and Perspective of Single-Molecule Spectroscopy for Chemistry

单分子光谱在过去三十年的时间里已经发展为不可或缺的重要研究手段,基于单分子光谱发展出的多种技术也在生物、化学、物理和材料领域取得卓越成果,特别是基于单分子光谱技术发展的超分辨显微成像技术在生物领域得到了广泛应用.相对而言,单分子光谱在化学领域的应用远未达到预期的广度本文综述了单分子光谱在化学领域中的重要应用,包括单分子成像、单分子传感、单分子催化和单分子光物理研究等方面.另外,本文还展望了单分子光谱在化学反应过程研究方面的应用潜力.

Single-molecule spectroscopy(SMS)has emerged as a powerful technique more than three decades after its initial optical detection in solid matrices.Over this period,numerous technological advancements have been made,leading to successful implementation of these methods across various scientific disciplines,such as biology,chemistry,physics,and materials.While SMS has found extensive utility in the field of biology,particularly in super-resolution imaging,its application in chemistry remains relatively limited.This review presents a comprehensive overview of the diverse applications of SMS in several areas,highlighting its potential applications in chemistry.Furthermore,we provide a brief perspective on the future development of SMS,emphasizing its promising prospects for advancing chemical research.