老年睡眠障碍患者睡眠质量与认知功能相关性分析

Correlation analysis of sleep quality and cognitive function in elderly patients with sleep disorders

目的 探讨老年睡眠障碍患者的睡眠质量与认知功能相关性分析。方法 回顾性分析145例老年睡眠障碍患者(老年睡眠障碍组)和同期体检无睡眠障碍的老年者111例(无睡眠障碍组),对比两组一般资料、简易智力状态检查量表(Mini-mental state examination,MMSE)和蒙特利尔认知评估量表(Montreal cognitive assessment scale,MoCA)评分和阳性率,经Pearman相关系数分析老年睡眠障碍患者与认知功能的相关性,并建立二元logistic回归分析睡眠障碍是否是影响老年患者认知功能障碍的独立危险因素。结果 老年睡眠障碍组的MMSE量表和MoCA量表相关评分显著低于无睡眠障碍组(P<0.05);老年睡眠障碍组的MMSE阳性率、MoCA阳性率均显著高于无睡眠障碍组(P<0.05);经Pearman相关系数分析,老年患者的睡眠障碍与MMSE阳性、MoCA阳性呈负相关(r=-0.658、-0.712,P<0.001);通过二元logistic回归分析显示,睡眠障碍为影响老年患者认知功能水平的独立危险因素(P<0.05)。结论 老年患者睡眠障碍与认知功能水平存在一定相关性,且是影响老年患者认知功能水平的独立危险因素。

Objective To explore the correlation between sleep quality and cognitive function in elderly patients with sleep disorders.Methods A retrospective analysis was performed on 145 elderly patients with sleep disorders(elderly sleep disorder group) and 111 elderly subjects without sleep disorders(non-sleep disorder group).The general data,scores and positive rates of Mini-Mental State Examination(MMSE) and Montreal Cognitive Assessment(MoCA) were compared between the two groups.The correlation between sleep disorder and cognitive function was analyzed by Pearman correlation coefficient,and binary logistic regression analysis was established to analyze whether sleep disorder was an independent risk factor affecting the cognitive dysfunction of elderly patients.Results The scores of MMSE scale and MoCA scale in elderly sleep disorder group were significantly lower than those in non-sleep disorder group(P<0.05),and the positive rates of MMSE and MoCA were significantly higher than those in non-sleep disorder group(P<0.05).According to Pearman correlation coefficient analysis,sleep disorder in elderly patients was negatively correlated with positive MMSE and positive MoCA(r=-0.658,-0.712,P<0.001).Binary Logistic regression analysis showed that sleep disorder was an independent risk factor affecting the cognitive function of elderly patients(P<0.05).Conclusion Sleep disorder in elderly patients has a certain correlation with cognitive function,and it is an independent risk factor affecting the cognitive function in elderly patients.