黏性骨在口腔种植及牙周领域中的研究进展

Progress of research on sticky bone in oral implant and periodontology

黏性骨由自体血小板浓缩物与颗粒骨移植材料交联而成,具有良好的可塑性和稳定性,可以适应多种骨缺损区形态并维持成骨空间;同时,源于自体血小板浓缩物的白细胞和多种生长因子的释放促进了血管生成和组织愈合。目前,黏性骨已逐渐应用于口腔种植和牙周领域并取得了积极效果。本文阐述了黏性骨的组成、制备方式和作用机制,并对其在牙槽骨增量、即刻种植、牙槽嵴保存、上颌窦底提升以及牙周手术中的应用进行综述,旨在为进一步的机制研究和临床应用提供参考。

Sticky bone comprises autogenous platelet concentrates and bone-particle grafts.It exhibits favorable plasticity and stability for fitting various bone defects and maintaining bone-regeneration space.Angiogenesis and tissue healing are promoted by the release of leukocytes and various growth factors from autogenous platelet concentrates.Sticky bone is currently being gradually applied in oral implantology and periodontology,and positive results have been obtained.This review briefly describes the composition,preparation protocol,and mechanism of sticky bone.Its applications in alveolar bone augmentation,immediate implant placement,alveolar ridge preservation,maxillary sinus floor elevation,and periodontal surgery are also outlined.This work can serve as a reference for further research on sticky bone and its clinical application.