基于数据挖掘技术的肺结节常见证候诊断依据分析

Analysis of common syndromes diagnosis basis of pulmonary nodules based on data mining

[目的]初步确立肺结节常见证候诊断依据。[方法]基于746份肺结节临床资料,采用关联规则结合贝叶斯网络数据挖掘技术,分析肺结节常见证候中关联较强的症状群及其对该证候诊断的贡献度。[结果]各常见证候关系密切的症状群及其对证候的贡献度分别为:1)肺气虚证:乏力&神疲(0.22);2)肺脾气虚证:咳嗽&痰色白(0.27)、咳嗽&气短(0.19)、舌苔白腻&舌质淡(0.57)、舌质淡&脉细弱(0.36)、乏力&纳呆(0.14);3)痰浊阻肺证:咳嗽&痰色白(0.32)、胸闷&气短(0.19)。瘀阻肺络证尚未得到关系密切的症状群。[结论]基于症状群对常见证候的贡献度,初步确立诊断条件与依据,可为肺结节证候诊断标准的建立提供依据,对瘀阻肺络证有贡献度的症状群有待进一步研究。

[Objective]To preliminarily establish the diagnosis basis for common syndromes of pulmonary nodules.[Methods]The correlation between symptoms and their contribution to common syndromes was analyzed using association rules combined with a Bayesian network based on the clinical data of 746 clinical data of pulmonary nodules.[Results]Among the common syndromes,the closely related symptom groups and their contribution to the syndrome were as follows:1)lung qi deficiency syndrome:fatigue&spiritual tiredness(0.22);2)lung spleen qi deficiency syndrome:cough&white phlegm(0.27),cough&shortness of breath(0.19),white greasy tongue fur&thin tongue(0.57),thin tongue&fine weak pulse(0.36),fatigue&poor appetite(0.14);3)phlegm turbid obstructing the lung syndrome:cough&white phlegm(0.32),chest tightness&shortness of breath(0.19).The syndrome of stasis obstructing lung collateral has not yet obtained a closely related symptom group.Conclusion based on the contribution of symptom clusters to common syndromes,the preliminary establishment of diagnostic conditions and basis can provide an objective basis for the establishment of diagnostic criteria for pulmonary nodules syndromes.The symptom clusters that contribute to the stasis lung collateral syndrome need to be further studied.[Conclusion]Based on the correlated symptom clusters and their contribution to syndromes,the diagnostic basis for common syndromes of pulmonary nodules were formed,which can provide a basis for the establishment of diagnostic criteria for pulmonary nodule common syndromes.However,the symptom clusters that contribute to the stasis lung collateral syndrome need to be further studied.