毫火针配合隔物艾灸治疗脾胃虚寒型功能性消化不良的临床疗效

Clinical effect of moxibustion combined with moxibustion on functional dyspepsia of spleen and stomach deficiency cold type

[目的]探讨毫火针配合隔物艾灸治疗脾胃虚寒型功能性消化不良的临床疗效。[方法]选择2022年9月—2023年9月珠海市中西医结合医院收治的90例脾胃虚寒型功能性消化不良患者,随机分为两组。对照组(45例)采用毫火针治疗,观察组(45例)采用毫火针配合隔物艾灸治疗。比较症状评分,血清胃肠激素、炎症因子,生活质量,疗效和安全性。[结果]两组治疗后症状评分较治疗前降低(P<0.01);肿瘤坏死因子-α(TNF-α)、白细胞介素(IL)-6、IL-1β水平较治疗前降低(P<0.01),血清促胃液素(GAS)、胃动素(MTL)较治疗前增高(P<0.01);健康查简表(SF-36)评分均较治疗前增高(P<0.01)。观察组治疗后血清TNF-ɑ、IL-6、IL-1β水平低于对照组(P<0.01),GAS、MTL高于对照组(P<0.01);SF-36评分高于对照组(P<0.01)。观察组治疗总有效率高于对照组(77.78%vs. 93.33%,P<0.05)。[结论]毫火针配合隔物艾灸治疗更有助于改善胃肠动力,抑制炎症反应,提高脾胃虚寒型功能性消化不良的临床疗效和生活质量。

[Objective]To investigate the clinical effect of moxibustion combined with moxibustion on functional dyspepsia of spleen and stomach deficiency cold type.[Methods]The 90 patients with functional dyspepsia with spleen and stomach deficiency and cold in our hospital from September 2022 to September 2023 were randomly divided into two groups.The control group(45 cases)was treated with the flame needle,and the observation group(45 cases)was treated with the flame needle combined with moxibustion.Symptom scores,serum gastrointestinal hormones,inflammatory factors,quality of life,efficacy,and safety were compared.[Results]The symptom scores of the two groups decreased after treatment compared to before treatment(P<0.01).The level of TNF-ɑ,IL-6 and IL-1βdecreased compared to before treatment(P<0.01),while serum gastrin(GAS)and motilin(MTL)increased compared to before treatment(P<0.01).The scores on the SF-36 were higher than before treatment(P<0.01).The TNF-ɑof the observation group after TNF-ɑ,IL-6,IL-1βThe level was lower than that of the control group(P<0.01),while GAS and MTL were higher than those of the control group(P<0.01).The SF-36 score was higher than that of the control group(P<0.01).The total effective rate of the observation group was higher than that of the control group(77.78%vs.93.33%,P<0.05).[Conclusion]Moxibustion with moxibustion can improve gastrointestinal motility,inhibit inflammatory reaction and improve the clinical effect and quality of life of functional dyspepsia with spleen and stomach deficiency and cold.