病毒性肝炎相关血常规及生化检验项目的应用价值和检出率观察

Application value and detection rate of blood routine and biochemical test items related to viral hepatitis

目的探讨病毒性肝炎相关血常规及生化检验项目的应用价值和检出率。方法选取2020年3月至2021年3月枣庄市立医院收治的70例病毒性肝炎患者作为观察组,另选取同期70名健康体检者作为对照组。两组均行血常规检验、生化检验,比较两组、慢性乙肝与慢性丙肝患者血常规及生化检验项目结果,比较血常规及生化检验项目对病毒性肝炎的检出率。结果观察组中性粒细胞百分比、WBC、血小板计数(PLT)水平均低于对照组,淋巴细胞百分比高于对照组,差异有统计学意义(P<0.05)。观察组丙氨酸氨基转移酶(ALT)、总胆红素(TBIL)水平均高于对照组,白蛋白(ALB)水平、肝功能白球比(A/G)均低于对照组,差异有统计学意义(P<0.05)。慢性乙肝患者ALT水平、TBIL水平、中性粒细胞百分比、淋巴细胞百分比、PLT均低于慢性丙肝患者,ALB水平、A/G、WBC均高于慢性丙肝患者,差异有统计学意义(P<0.05)。70例病毒性肝炎患者实施血常规联合生化检验项目,共检出67例,检出率为95.71%,均高于单一血常规、生化项目检验的68.57%、77.14%(P<0.05)。结论血常规联合生化检验项目对病毒性肝炎具有显著的诊断价值,可反映患者血细胞功能情况和生化检验指标,为临床诊疗活动提供科学依据,改善患者预后。

Objective To investigate the application value and detection rate of blood routine and biochemical test items related to viral hepatitis.Methods Atotal of 70 patients with viral hepatitis admitted to Zaozhuang Municipal Hospital from March 2020 to March 2021 were selected as the observation group,and 70 healthy subjects were selected as the control group.The two groups were performed routine blood test and biochemical test items,the results of routine blood test and biochemical test items were compared between the two groups,chronic hepatitis B and chronic hepatitis C patients,and the detection rate of routine blood test and biochemical test items for viral hepatitis was compared.Results The percentage of neutrophils,WBC and platelet count(PLT)in the observation group were lower than those in the control group,and the percentage of lymphocytes was higher than that in the control group,the differences were statistically significant(P<0.05).The levels of alanineaminotransferase(ALT)and total bilirubin(TBIL)in the observation group were higher than those in the control group,and the levels of albumin(ALB)and albumin/globulin(A/G)were lower than those in the control group,the differences were statistically significant(P<0.05).The levels ofALT,TBIL,neutrophil percentage,lymphocyte percentage and PLT in patients with chronic hepatitis B were lower than those in patients with chronic hepatitis C,and the levels ofALB,A/G andWBC were higher than those in patients with chronic hepatitis C,the differences were statistically significant(P<0.05).Among 70 patients with viral hepatitis,67 cases were detected by routine blood test combined with biochemical test,detection rate of 95.71%,which was higher than that 68.57%and 77.14%of single routine blood test and biochemical test(P<0.05).Conclusion Blood routine combined with biochemical test items have significant diagnostic value for viral hepatitis,which can reflect the blood cell function and biochemical test indicators of patients,provide scientific basis for clinical diagnosis and treatment activities,achieve the purpose of early detection,accurate diagnosis and timely treatment of diseases,and improve the prognosis of patients.