摘要
巨噬细胞胞外诱捕网(METs)是由巨噬细胞产生的细胞外纤维网状结构。METs在动脉粥样硬化、心肌梗死和其他心血管疾病(CVDs)的发生和发展中起到重要作用。本文对METs在CVDs中的作用机制、未来的研究方向及将其作为临床疾病潜在治疗靶点的可能性进行阐述。
Macrophage extracellular traps(METs)are extracellular fibrous web-like structures produced by macrophages.METs play a crucial role in the development and progression of various cardiovascular diseases(CVDs),including atherosclerosis and myocardial infarction.This article summarizes the mechanism of METs in CVDs,future research directions and the possibility of using METs as potential therapeutic targets for clinical diseases.
作者
李星辰
吴倩倩
赵可心
王润森
王晓萍
LI Xingchen;WU Qianqian;ZHAO Kexin;WANG Runsen;WANG Xiaoping(Henan Key Laboratory of Medical Tissue Regeneration,Xinxiang Medical University,Xinxiang 453003,Henan Province,China;Department of Human Anatomy and Histoembryology,School of Basic Medical Sciences,Xinxiang Medical University,Xinxiang 453003,Henan Province,China;The Fourth Clinical College,Xinxiang Medical University,Xinxiang 453003,Henan Province,China;Hongyi College,Xinxiang Medical University,Xinxiang 453003,Henan Province,China)
出处
《新乡医学院学报》
CAS
2024年第7期614-618,共5页
Journal of Xinxiang Medical University
基金
国家自然科学基金资助项目(编号:82300386)。
关键词
巨噬细胞
胞外诱捕网
心血管疾病
macrophages
extracellular traps
cardiovascular diseases
