≥40岁女性的体质指数及身体肥胖指数与代谢综合征的关系分析

Analysis of the relationship between body mass index,body adiposity index,and metabolic syndrome in women over 40 years old

为评估40岁以上女性人群的体质指数(BMI)及身体肥胖指数(BAI)与代谢综合征(MS)之间的关系,2022年7月,采用病例-对照研究,选择福建省宁德市的社区体检人群中被诊断为MS的246例患者为病例组,对照组按照同时期、同地区、同年龄、同性别进行1∶1配对,对病例组和对照组调查对象的个人信息、人体形态学测量指标及血样实验室检测指标进行对比分析.结果显示,病例组的空腹血糖、餐后2 h血糖、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL-C)、收缩压、舒张压、BAI、BMI和腰围(WC)均高于对照组,差异有统计学意义(P<0.05).相关性的分析结果表明,MS患者BMI与空腹血糖、餐后2 h血糖的相关系数分别位0.417和0.314(P<0.001),BAI与空腹血糖、餐后2 h血糖的相关系数更高,r值分别达到0.526和0.441(P<0.001).以是否MS为因变量,校正了年龄等混杂因素后,BMI为MS患病的危险因素,OR(95%CI)为1.223(1.163,1.287),BAI的OR(95%CI)为1.728(1.548,1.929).研究表明,相比于BMI,BAI与MS的代谢指标的相关性更有优势,能较好地预测40岁以上女性MS人群及其代谢指标的异常.

To evaluate the relationship between body mass index(BMI),body adiposity index(BAI),and meta-bolic syndrome(MS)in women over the age of 40,a case-control study was carried out.246 patients diagnosed with MS from the community physical examination population in Ningde city of Fujian province were selected as the case group.The control group was paired 1∶1 according to the same period,region,age,and gender.The personal information,human morphology measurement indicators,and blood sample laboratory testing indica-tors of the case group and control group were analyzed.The data were analyzed using SPSS 21.0 software.Re-sults show that the fasting blood glucose,2-hour postprandial blood glucose,total cholesterol(TC),triglycer-ides(TG),low-density lipoprotein(LDL-C),systolic blood pressure,diastolic blood pressure,BAI,BMI,and waist circumference(WC)of the case group were all higher than those of the control group,with statistically sig-nificant differences(P<0.05).The correlation analysis results show that the correlation coefficients between BMI and fasting blood glucose and 2-hour postprandial blood glucose in MS patients are 0.417 and 0.314(P<0.001),respectively.The correlation coefficients between BAI and fasting blood glucose and 2-hour postpran-dial blood glucose are higher,with r values reaching 0.526 and 0.441(P<0.001),respectively.After adjusting for confounding factors such as age,BMI was the risk factor for MS,with an OR(95%CI)of 1.223(1.163,1.287)and BAI(95%CI)of 1.728(1.548,1.929).In conclusion,compared with BMI,the correlation between BAI and metabolic indicators of MS is more advantageous.On the other hand,similar to BMI,BAI can also bet-ter predict the abnormalities of metabolic indicators in women over 40 years old with MS.