微针治疗斑秃的研究进展

Microneedling in alopecia areata:a review

斑秃是一种非瘢痕性毛发脱失性疾病,个别患者可出现头发完全脱失、甚至全身毳毛全部脱落。斑秃常使患者的生活质量受到严重影响。斑秃的病因目前暂不明确,可能与遗传因素、精神因素、环境因素和免疫等有关。斑秃的治疗方法包括糖皮质激素、局部免疫疗法、免疫抑制剂、米诺地尔和小分子药物、生物制剂及自体制剂等,但目前没有能彻底治愈的方法,也没有普遍认可维持长期缓解的治疗方案。近来,随着微针在斑秃治疗中的广泛应用,一些传统治疗方法无效的斑秃患者也能够得到较好的病情改善。兹就微针治疗斑秃的研究进展进行综述。

Alopeciaareataisanon-cicatricial hair lossdisease.Someindividualswith alopeciaareatamay experiencecompletehair loss or even experience vellus hair loss all over their body.The quality of life of patients with alopecia areata is often severely affected.The etiology of alopecia areata remains unclear,but it may be related to genetic factors,mental factors,environmental factors,immune factors and others.The current treatments for alopecia areata include corticosteroids,local immunotherapy,immunosuppressants,minoxidil,small molecular drugs,biological agents,autologous preparations and others.However,there is currently no radical cure for alopecia areata,nor is there a generally accepted treatment for long-term remission.Recently,with the widespread application of microneedling in the treatment of alopecia areata,some patients with alopecia areata who failed to respond to traditional treatments can also get better improvement.This article reviews the research progress of microneedling in the treatment of alopecia areata.