昂丹司琼对降低剖宫产术后镇痛恶心呕吐及提升生活质量的研究

Study on Ondansetron Reducing Analgesia, Nausea and Vomiting after Cesarean Section and Improving Quality of Life

目的探究使用昂丹司琼降低剖宫产术后镇痛恶心呕吐及提升生活质量的效果。方法回顾性选取2022年1月—2023年6月广西壮族自治区桂东人民医院收治的100例剖宫产产妇的临床资料,根据预防性使用止吐药物的不同分成两组,其中A组65例(昂丹司琼4 mg+地塞米松5 mg),B组35例(地塞米松5 mg),对比两组术后恶心呕吐发生率、舒适度评分和生活质量评分。结果A组术后恶心呕吐发生率为6.15%,显著低于B组的22.86%,差异有统计学意义(χ^(2)=11.398,P<0.05);A组舒适度评分和生活质量评分显著高于B组,差异有统计学意义(P均<0.05)。结论预防性使用昂丹司琼能有效预防剖宫产术后镇痛恶心呕吐的发生,有助于提高患者舒适度和生活质量。

Objective To explore the effect of ondansetron on reducing analgesia,nausea and vomiting and improving quality of life after cesarean section.Methods Retrospectively selected clinical data of 100 cases of cesarean delivery admitted to Guidong People's Hospital of Guangxi Zhuang Autonomous Region from January 2022 to June 2023,and they were divided into two groups,according to the use of antiemetic drugs.There were 65 cases in group A(ondan⁃setron 4 mg+dexamethasone 5 mg)and 35 cases in group B(dexamethasone 5 mg).The incidence of postoperative nausea and vomiting,comfort score and quality of life score were compared between the two groups.Results The inci⁃dence of postoperative nausea and vomiting in group A was 6.15%,significantly lower than 22.86%in group B,and the difference was statistically significant(χ^(2)=11.398,P<0.05).The comfort score and quality of life score of group A were significantly higher than those of group B,and the differences were statistically significant(both P<0.05).Con⁃clusion Preventive use of ondansetron can effectively prevent the occurrence of analgesia,nausea and vomiting after cesarean section,and help to improve the comfort and quality of life of patients.