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CT功能成像在胃癌治疗前评估中的研究进展

Review on functional CT imaging for pretreatment assessment in gastric cancer
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摘要 胃癌的发病率和死亡率均居世界恶性肿瘤前列,目前增强CT是胃癌术前诊断与评估的主要手段,但其多基于形态学评估,无法进行定量分析。以能谱CT及CT灌注成像为代表的功能成像技术发展迅速,其具有多种精准定量参数,有望弥补常规CT的缺陷。本文对能谱CT及CT灌注成像的基础原理、其在胃癌诊断、病理分型、分级、分期的评估以及疗效预测等方面的研究展开综述,旨在提高CT功能成像在胃癌治疗前评估中的认识。 Both morbidity and mortality of gastric cancer are in the front rank among malignant tumors.At present,enhanced CT is served as an important imaging method for preoperative diagnosis and assessment of gastric cancer,but it is mostly based on morphological evaluation and unable to perform quantitative analysis.The functional imaging technology represented by energy spectral CT and CT perfusion imaging has a variety of quantitative parameters,which is expected to make up for the shortcomings of conventional CT.The review introduces the basic principles of energy spectral CT and CT perfusion imaging,and summarizes their applications in the diagnosis,pathological classification,grading,staging and efficacy prediction of gastric cancer,aiming to improve the understanding of functional CT imaging for the pretreatment assessment in gastric cancer.
作者 任铁柱 陈倩倩 张文娟 邓娟 苏鑫安 徐敏 徐媛 孙嘉晨 李玉凤 周俊林 REN Tiezhu;CHEN Qianqian;ZHANG Wenjuan;DENG Juan;SU Xinan;XU Min;XU Yuan;SUN Jiachen;LI Yufeng;ZHOU Junin(Department of Radiology,Lanzhou University Second Hospital/the Second Clinical Medical School,Lanzhou University/Key Laboratory of Medical Imaging of Gansu Province/Gansu International Scientific and Technological Cooperation Base of Medical Imaging Artificial Intelligence,Lanzhou 730030,China;Department of Rheumatology,the First Hospital of Lanzhou University,Lanzhou 730030,China)
出处 《中国医学物理学杂志》 CSCD 2024年第7期836-841,共6页 Chinese Journal of Medical Physics
基金 国家自然科学基金(82071872,82102151) 甘肃省省级人才项目(青年个人项目)(甘组通字[2024]4号)。
关键词 胃癌 能谱CT CT灌注 治疗前评估 综述 gastric cancer energy spectral CT CT perfusion pretreatment assessment review
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