药品全生命周期视角的药物经济学评价应用研究

Study of the application of pharmacoeconomic evaluation from the perspective of drug life cycle

药品全生命周期的每个阶段均能够反映药品的不同价值。药物经济性评价是评估药品价值的重要手段,目前多应用于医保目录谈判准入工作,其他领域应用场景较少。该研究基于药品全生命周期视角,梳理国内外药物经济学评价应用情况的相关文献,从研发立项、上市定价和医保目录准入、药品入院和临床使用、药品的上市后变更和再注册、退市4个阶段研究药物经济学评价的应用情况,分析药品全生命周期药物经济学评价应用的环境,提出应加强药物经济学评价应用的政策支持力度、形成药品全生命周期的各阶段药物经济学评价范式、注重药物经济学药品全生命周期多角度协调机制,以期为我国药物经济学的学科建设和良性发展提供参考。

Each life-cycle stage of drugs can reflect the different value of drugs,and drug economic evaluation is an important means to evaluate the value of drugs.At present,pharmacoeconomic evaluation is mainly used in the negotiation of access to the medical insurance catalogue,and there are few application scenarios in other fields.Based on the perspective of drug life cycle,this study reviews domestic and foreign literature on the application of pharmacoeconomic evaluation.The application of pharmacoeconomic evaluation is studied from four stages:research and development and project approval,listing pricing and access to the medical insurance catalogue,admitted to hospital and clinical use of drugs,drug post-marketing change and re-registration,and delisting.This paper analyzesthe application environment of pharmacoeconomic evaluation in the drug life cycle,and proposes to strengthen the policy support for the application of pharmacoeconomic evaluation,form a paradigm for pharmacoeconomic evaluation at each stage of the drug life cycle,and focus on the multi-perspective coordination mechanism of pharmacoeconomic drug life cycle,in order to provide references for the discipline construction and benign development of pharmacoeconomics in our country.