摘要
非酒精性脂肪性肝病(NAFLD)为成人2型糖尿病(T2DM)及糖尿病前期常见伴发疾病,T2DM/NAFLD患者为心血管疾病的高危人群,NAFLD及其相关肝纤维化的发生和发展、心血管疾病及其相关死亡严重影响患者预后。2024年美国糖尿病学会《糖尿病标准化管理指南》针对T2DM及糖尿病前期人群NAFLD,以及肝纤维化的筛查、评估、治疗及管理提出相关建议。在改善生活方式基础上,减重、控制血糖是减缓肝脏炎症及肝纤维化进展、降低心血管疾病风险的重要措施。
Non-alcoholic fatty liver disease(NAFLD)is a common concomitant disease in adults with type 2 diabetes mellitus(T2DM)and prediabetes.Therefore,T2DM/NAFLD patient populations are at high risk for cardiovascular disease.The occurrence and progression of non-alcoholic fatty liver disease-related liver fibrosis and cardiovascular disease have a severe impact on the patient’s prognosis and mortality rate.The American Diabetes Association's 2024"Guidelines for the Standardized Management of Diabetes"put forward recommendations relevant to the screening,evaluation,treatment,and management of NAFLD in T2DM and prediabetic populations,as well as liver fibrosis.The important measures for decelerating liver inflammation and fibrosis progression and the risk of cardiovascular disease are based on improvements in lifestyle methods,weight loss,and blood sugar control.
作者
倪文婧
李婕
南月敏
Ni Wenjing;Li Jie;Nan Yuemin(Department of Infectious Diseases,Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine,Nanjng 210008,China;Department of Infectious Diseases,Nanjing Drum Tower Hospital,Affiliated Hospital of Medical School,Nanjing University,Nanjing 210008,China;Department of Traditional and Western Medical Hepatology,Hebei Medical University Third Hospital,the Key Laboratory of Hepatic Fibrosis Mechanisms of Chronic Liver Diseases,Hebei Province,Hebei International Science and Technology Cooperation Base--Hebei International Joint Research Center for Molecular Diagnosis of Liver Cancer,Shijiazhuang 050051,China)
出处
《中华肝脏病杂志》
CAS
CSCD
北大核心
2024年第6期504-507,共4页
Chinese Journal of Hepatology
基金
国家自然科学基金(82170609、81970504)。
关键词
非酒精性脂肪性肝病
2型糖尿病
心脏代谢风险因素
综合管理
诊断
治疗
Non-alcoholic fatty liver disease
Diabetes mellitus type 2
Cardiometabolic risk factors
Comprehensive management
Diagnosis
Treatment
