焦虑障碍的脑电生理研究进展

Research progress of eletroencephalography in anxiety disorders

焦虑障碍临床表现复杂,目前缺乏诊断以及疗效预测相关的神经生物学指标。脑电图是一种非侵入性的神经电生理检测工具,具有较高的时间分辨率,能锁时反映焦虑障碍认知损害的时间进程。现对焦虑障碍的时域、频域、功能连接脑电特征的相关研究进行综述,探索焦虑障碍自上而下和自下而上的认知加工异常,为进一步明确焦虑障碍的神经心理机制以及探索焦虑障碍预测、诊断、预后相关的神经生物学客观指标提供参考。

The clinical manifestations of anxiety disorders are complex,and there is currently a lack of neurobiological indicators related to diagnosis and efficacy prediction.Electroencephalogram(EEG)is a non-invasive neurophysiological detection tool with high temporal resolution,which can reflect the temporal progression of cognitive impairment in anxiety disorders.This article reviews the relevant research on the temporal,frequency,and functional connectivity EEG characteristics of anxiety disorders,exploring the cognitive processing abnormalities of anxiety disorders from top-down and bottom-up.The aim of this review was to provide reference for further clarifying the neuropsychological mechanisms of anxiety disorders and exploring objective neurobiological indicators related to the prediction,diagnosis,and prognosis of anxiety disorders.