抗生素骨水泥覆盖治疗慢性难愈性创面30例

Report of 30 Cases of Antibiotic-Loaded Bone Cement Coverage for the Treatment of Chronic Refractory Wounds

目的:观察抗生素骨水泥覆盖治疗慢性难愈合创面的疗效。方法:选择2020年1月至2023年1月收治的30例慢性难愈性创面患者,给予抗生素骨水泥覆盖治疗,并对疗效进行评价。结果:30例患者最终治愈21例(70.00%),有效7例(23.30%),无效2例(6.67%),总有效率为93.30%。平均清创次数为(1.63±1.13)次,术前及术后3周白细胞计数、C反应蛋白、红细胞沉降率比较差异均有统计学意义(P<0.05)。结论:抗生素骨水泥覆盖治疗慢性难愈性创面疗效确切,能控制创面感染,治疗效果令人满意。

Objective:To investigate the efficacy of treatment of chronic refractory wounds with antibiotic-loaded bone cement coverage.Methods:30 patients with chronic refractory wounds between January 2020 and January 2023 who were treated with antibiotic-loaded bone cement therapy were selected for the study to evaluate its efficacy.Results:The final cure rate of the 30 patients included in the study was 21(70.00%),7(23.30%)effective and 2(6.67%)ineffective,that is,the overall efficacy was 93.30%.The mean number of debridements was(1.63±1.13)times,and there were differences in leukocyte count,C-reactive protein and erythrocyte sedimentation rate before surgery and 3 weeks after surgery(P<0.05).Conclusion:The efficacy of antibiotic-loaded bone cement coverage in the treatment of chronic refractory wounds is accurate,provides effective control of wound infection and has a satisfactory therapeutic effect.