2940 nm铒激光微剥脱联合外敷复方桐叶烧伤油治疗面部凹陷性痤疮瘢痕的临床研究

Clinical study of 2940 nm erbium laser micro peeling combined with topical complex tongye burn oil for the treatment of facial atrophic acne scars

目的 探讨铒激光微剥脱联合外敷复方桐叶烧伤油在面部凹陷性痤疮瘢痕中的应用效果及可能的作用原理。方法 选取自2020年7月至2022年12月,百色市人民医院烧伤整形美容外科、创面修复科收治的63例面部凹陷性痤疮瘢痕患者,随机分为观察组(32例)和对照组(31例)。观察组采用2940 nm铒激光微剥脱联合外用复方桐叶烧伤油治疗,对照组采用2940 nm铒激光微剥脱治疗。1个月治疗1次,4次为1个疗程。治疗后3个月后开始随访观察,比较两组患者治疗前后痤疮瘢痕权重评分(Echelle d'evaluation clinique des cicatrices d'acne, ECCA)、症状恢复时间、不良反应情况。结果 63例患者均完成了治疗方案。观察组总有效率(87.50%)较对照组(77.42%)高(P<0.05);两组治疗后ECCA评分均较本组治疗前降低,且观察组低于对照组(P<0.05);观察组水肿时间、红斑持续时间、结痂时间均较对照组缩短(P<0.05);两组治疗期间不良反应发生率比较,差异有统计学意义(P<0.05)。结论 采用外敷复方桐叶烧伤油能有效辅助2940 nm铒激光微剥脱治疗面部痤疮瘢痕,增强治疗效果,缩短恢复时间,减少不良反应。

Objective To investigate the application effect and potential mechanisms of erbium laser micro-peeling combined with topical complex Tongye burn oil in the treatment of facial atrophic acne scars.Methods A total of 63 patients with facial atrophic acne scars from July 2020 to December 2022 at Baise People's Hospital were randomly divided into an observation group(n=32)and a control group(n=31).The control group received treatment with 2940 nm erbium laser micro-peeling,while the observation group received treatment with 2940 nm erbium laser micro-peeling combined with topical complex Tongye burn oil.pre-treatment and post-treatment acne scar weight scores(ECCA),symptom recovery time,and adverse reactions were compared between the two groups.Results All patients complated the treatmant.After treatment,the total effective rate in the observation group was 87.50%,which was significantly higher than the 77.42%in the controlgroup control group(P<0.05).Both groups showed a reduction in ECCA scores after treatment,with the observation group having lower scores than the control group(P<0.05).The observation group had a shorter duration of edema,erythema,and scab formation compared to the control group(P<0.05).There was a statistically significant difference in the incidence of adverse reactions during the treatment period between the two groups(P<0.05).Conclusion Topical complex Tongye burn oil can effectively assist in the treatment of facial acne scars with 2940 nm erbium laser micro-peeling,enhancing treatment efficacy and shortening recovery time and reducing adverse reactions.