人工肝支持系统相关血源性病原体感染预防与控制专家共识

Expert consensus on the prevention and control of blood borne pathogen infections related to artificial liver support

人工肝支持系统(简称人工肝)是目前治疗肝衰竭的重要手段,因部分患者为血源性病原体携带者或感染者,在治疗过程中患者及医护人员存在血源性病原体感染的风险。我国人工肝相关血源性病原体感染防控策略相关研究处于起步阶段,缺乏规范性、一致性认识。为此,中华护理学会传染病护理专业委员会、湖南省护理学会传染病护理专业委员会组织国内专家,基于国家医院感染防控的相关法律、法规,参考国内外人工肝治疗及血源性病原体感染防控现状,结合我国临床诊疗指南及最佳临床实践证据要求,经反复讨论、修改形成本共识。共识通过对人工肝治疗各环节的风险评估,制定规避风险的安全操作流程,主要包括人工肝室设置、制度管理要求、治疗过程基于患者及医护人员防控细则、暴露处理流程等25项专家共识内容,为人工肝相关血源性病原体感染预防与控制提供临床指导,规避血源性病原体职业暴露及院内感染风险,保障患者及医护人员安全。

Artificial liver support is currently an important means of treating liver failure.As some patients are carriers or infected with blood borne pathogens,both patients and medical staff are at risk of blood borne pathogen infection during the process of extracorporeal circulation.The research on prevention and control strategies for blood borne pathogens related to artificial liver support in China is still in its early stages,lacking standardized and consistent understanding.Hence,this consensus is formed with the effort of nursing experts who were organized by the Infectious Disease Nursing Professional Committee of Chinese Nursing Association organized domestic experts,based on the relevant laws and regulations of national hospital infection prevention and control.Which is also be guided by domestic and foreign literatures related to the current situation of artificial liver support treatment and blood borne pathogen infection prevention and control,and combined with China's clinical diagnosis and treatment guidelines and best clinical practice evidence requirements.Consensus provides clinical guidance for the prevention and control of blood borne pathogen infections related to artificial liver support through risk assessment of various stages of artificial liver support treatment,and the development of safe operation procedures to avoid risks,including the setting of artificial liver rooms,institutional management requirements,prevention and control rules based on patients and medical staff during the treatment process,exposure handling procedures and other 25 expert consensus content.It aims to avoid occupational exposure to blood borne pathogens and hospital acquired infection risks,and ensure the safety of patients and medical staff.