国内亚健康状态中医临床试验的文献计量学研究

Bibliometrics study of Chinese medicine clinical intervention trial of sub-health status in China

[目的]探讨国内亚健康状态中医临床试验方法、干预措施及目前研究热点分布领域,为日后临床研究及干预提供参考。[方法]采用循证医学定性系统综述研究方法,检索中国知网(CNKI)、维普(VIP)及万方数据库(WANFANG DATA)文献,应用Note Express 3.2.0软件结合人工阅读文章的方式对检索的文献进行筛选,分别从文献研究方法、干预措施、有效率、受试人群、发表时间、核心作者、期刊分布、基金分布等方面进行定性系统综述分析。[结果]纳入141篇文献,近5年发文量明显降低,可见近几年国内对亚健康状态中医临床试验的关注度呈下降趋势;临床试验研究方法以随机对照试验居多,占总文献的78.72%,但阐明随机化方法的仅占32.43%,且样本含量普遍较低,以致文章可信度低;共有38种结局指标,累计频次279次,说明中医临床试验已有较成熟体系;涉及作者389位,根据普赖斯定律尚未形成核心作者群;涉及期刊67种,尚未形成核心期刊;省级基金项目最多,国家级次之;高频关键词分析,亚健康仍为热点词,其次为亚健康状态,临床疗效;受试人群有25种,较为广泛。干预措施以中药治疗者居多,其次为中医综合疗法、中医推拿法,由此可见,中药在本研究所提及的众多干预措施中是认可度最高的。[结论]研究表明,亚健康状态中医临床试验研究热度有所降低,但受试人群比较广,相对具有代表性,现亚健康人群较多,应重视亚健康状态临床试验的研究及研究的严谨性。

[Objective]To explore the quality of research methods and the distribution of current research hotspots in Chinese clinical controlled trials of sub-health.[Methods]CNKI,VIP and Wanfang Data were searched,and the articles were screened by note express 3.2.0 combined with manual reading.The research methods,publication time,core authors,journal distribution,fund distribution,intervention measures,subjects and efficiency were analyzed System overview analysis.[Results]141 articles were included in the study,and the number of articles published in the past five years was significantly reduced.It can be seen that in recent years,the attention on clinical trials of Chinese medicine in sub-health state was on the decline trend;most of the clinical trials were randomized controlled trials,accounting for 78.72%of the total literatures,but only 34.23%of the total literatures clarified randomized methods,and the sample content was generally low,and the article credibility was low;389 authors were involved,according to price The law has not yet formed a core author group;67 journals have not yet formed a core journal;the provincial fund projects are the most,followed by the national level;high frequency keyword analysis,sub-health is still a hot word,followed by sub-health status,clinical efficacy;25 subjects,more extensive.[Conclusion]The research shows that the research heat of Chinese medicine sub-health clinical trial is much lower,but the subjects are relatively broad and representative,and there are more sub-health people now,so we should pay attention to the research and research preciseness of Chinese medicine sub-health clinical trial.