经化学治疗肺癌患者自我调节疲劳现状及影响因素分析

Analysis of self-regulatory fatigue status and influencing factors in lung cancer patients undergoing chemotherapy

目的 探讨化学治疗(简称化疗)肺癌患者的自我调节疲劳现状,并分析其相关影响因素。方法 本研究为横断面研究。采用便利抽样法,选取2022年8月—2023年2月于北京市应急总医院呼吸内科住院的肺癌化疗患者为研究对象,按照纳入与排除标准,最终纳入255例。采用自制一般资料调查表、慢性病患者健康素养量表(HLSCP)、社会支持评定量表(SSRS)、自我调节疲劳量表(SRFS)分别对患者进行问卷调查。采用独立样本t检验或单因素方差分析探讨肺癌化疗患者自我调节疲劳得分在一般资料中的差异;采用Pearson相关分析探讨自我调节疲劳与健康素养、社会支持的相关性;采用多元线性回归分析肺癌化疗患者自我调节疲劳的影响因素。结果 255例肺癌化疗患者的HLSCP得分平均(78.96±10.41)分,SSRS得分平均(39.27±5.34)分,SRFS得分平均(53.08±4.95)分。单因素分析显示自我疲劳得分在年龄、受教育程度、家庭人均月收入、病程及疼痛程度之间比较,差异均有统计学意义(P均<0.05)。Pearson相关分析结果显示:自我调节疲劳与健康素养、社会支持均呈负相关(r值分别为-0.491、-0370,P均<0.001)。多元线性回归分析结果显示:受教育程度、健康素养、疼痛程度、社会支持是影响肺癌化疗患者自我调节疲劳的主要因素,解释总变异量的37.9%。结论 肺癌化疗患者自我调节疲劳处于中等偏高水平,医务人员应针对患者的受教育程度、健康素养、疼痛程度及社会支持方面重点进行改善。

Objective To investigate self-regulatory fatigue status of lung cancer patients undergoing chemotherapy(referred to as chemotherapy)and analyze its related influencing factors.Method This study is a cross-sectional study.Using convenience sampling,255 lung cancer patients undergoing chemotherapy admitted to the department of respiratory medicine of Beijing Emergency General Hospital from August 2022 to February 2023 were selected as the research subjects.According to the inclusion and exclusion criteria,a self-made general information questionnaire,health literacy scale for chronic patients(HLSCP),social support rating scale(SSRS),and self-regulatory fatigue scale(SRFS)were used for questionnaire surveys.Independent sample t test or one-way analysis of variance were used to explore the differences in self-regulatory fatigue scores among lung cancer patients undergoing chemotherapy in terms of general information.Pearson correlation analysis was used to explore the correlation between self-regulatory fatigue and health literacy and social support.Multiple linear regression analysis was used to identify the influencing factors of self-regulatory fatigue in lung cancer patients undergoing chemotherapy.Results The average HLSCP score of 255 lung cancer patients undergoing chemotherapy was(78.96±10.41)points,SSRS score was(39.27±5.34)points,and SRFS score was(53.08±4.95)points.Univariate analysis showed that there were statistically significant differences in self-regulatory fatigue scores among patients of different ages,education levels,average monthly family income,course of disease,and pain intensity(all P<0.05).Pearson correlation analysis results showed a negative correlation between self-regulatory fatigue and health literacy,social support(r=-0.491,-0.370,respectively;all P<0.001).Multiple linear regression analysis results indicated that education level,health literacy,pain intensity,and social support were the main factors influencing self-regulatory fatigue in lung cancer patients underging chemotherapy,explaining 37.9%of the total variance.Conclusion Self-regulatory fatigue in lung cancer patients undergoing chemotherapy is at a moderately high level.Healthcare providers should focus on improving patients'education level,health literacy,pain intensity,and social support.