hs-cTnI、Myo、CK-MB联合检测在急性心肌梗死中的诊断价值

Diagnostic Value of hs-cTnI,Myo and CK-MB Combined Detection in Acute Myocardial Infarction

目的:探讨高敏心肌肌钙蛋白I(hs-cTnI)、肌红蛋白(Myo)及肌酸激酶同工酶(CK-MB)联合检测在急性心肌梗死中的诊断价值。方法:选取2021年6月—2022年6月仁怀市人民医院收治的100例急性心肌梗死患者作为观察组,另选取同期100例住院患者作为对照组。两组均检测hs-cTnI、Myo、CK-MB水平。比较两组hs-cTnI、Myo、CK-MB水平,分析hs-cTnI、Myo、CK-MB及三者联合检测在急性心肌梗死中的诊断价值。结果:观察组hs-cTnI、Myo、CK-MB水平均高于对照组,差异有统计学意义(P<0.05)。绘制受试者工作特征(ROC)曲线显示,hs-cTnI、Myo、CK-MB联合检测诊断急性心肌梗死的曲线下面积(AUC)最高。结论:hs-cTnI、Myo、CK-MB在急性心肌梗死诊断中具有一定价值,联合检测价值最高,有助于患者尽早开展针对性治疗,以改善预后。

Objective:To investigate the diagnostic value of high-sensitivity myocardium troponin I(hs-cTnI),myoglobin(Myo)and creatine kinase isoenzyme(CK-MB)in acute myocardial infarction.Method:A total of 100 patients with acute myocardial infarction admitted to Renhuai City People's Hospital from June 2021 to June 2022 were selected as the observation group,and another 100 hospitalized patients during the same period were selected as the control group.The hs-cTnI,Myo and CK-MB levels were detected in both groups.The levels of hs-cTnI,Myo and CK-MB were compared between the two groups,the diagnostic value of hs-cTnI,Myo,CK-MB and their combined detection in acute myocardial infarction was analyzed.Result:The levels of hs-cTnI,Myo and CK-MB in observation group were higher than those in control group,and the differences were statistically significant(P<0.05).The receiver operating characteristic(ROC)curve showed that the combined detection of hs-cTnI,Myo and CK-MB had the highest area under cruve(AUC)in the diagnosis of acute myocardial infarction.Conclusion:hs-cTnI,Myo and CK-MB have certain value in the diagnosis of acute myocardial infarction,and their combined detection has the highest value,which helps patients to carry out targeted treatment as soon as possible to improve the prognosis.