早期个体化肠内营养在胃肠手术患者中的应用

Application of Early Individualized Enteral Nutrition in Patients Undergoing Gastrointestinal Surgery

目的:探讨早期个体化肠内营养(enteral nutrition,EN)在胃肠手术患者中的应用。方法:选取2021年12月—2022年11月亳州市中医院普通外科收治的100例胃肠手术患者。根据随机数表法将其分为试验组和对照组,各50例。试验组术后给予早期个体化EN,对照组术后给予肠外营养(parenteral nutrition,PN)。比较两组术前1 d、术后7 d营养指标,肠道恢复指标,术前1 d、术后1 d、术后7 d免疫功能。结果:术后7 d,试验组前白蛋白、转铁蛋白水平均高于对照组,差异有统计学意义(P<0.05)。试验组肛门排气时间早于对照组,住院时间短于对照组,住院费用少于对照组,差异有统计学意义(P<0.05)。术后7 d,试验组CD3^(+)、CD4^(+)及CD4^(+)/CD8^(+)均明显高于对照组,差异有统计学意义(P<0.05)。结论:根据个体情况在胃肠术后实施早期个体化EN能够促进胃肠功能的快速恢复,从而改善患者的营养状况及免疫功能。

Objective:To explore the application of early individualized enteral nutrition(EN)in patients undergoing gastrointestinal surgery.Method:A total of 100 patients with gastrointestinal surgery admitted to the General Surgery Department of Bozhou Hospital of Traditional Chinese Medicine from December 2021 to November 2022 were selected.According to random number table method,they were divided into experimental group and control group,50 cases in each group.The experimental group was given early individualization EN and the control group was given parenteral nutritional(PN)support.Nutritional indexes,intestinal recovery indexes 1 d before surgery and 7 d after surgery,and immune function 1 d before surgery,1 d after surgery,and 7 d after surgery were compared between the two groups.Result:After 7 d of surgery,the levels of prealbumin and transferrin in experimental group were higher than those in control group,the differences were statistically significant(P<0.05).The anal exhaust time of experimental group was earlier than that of control group,the hospitalization time was shorter than that of control group,and the hospitalization cost was less than that of control group,the differences were statistically significant(P<0.05).After 7 d of surgery,CD3^(+),CD4^(+) and CD4^(+)/CD8^(+)in experimental group were significantly higher than those in control group,the differences were statistically significant(P<0.05).Conclusion:Implementing early individualization EN after gastrointestinal surgery based on individual circumstances can promote rapid recovery of gastrointestinal function,thereby improving the nutritional status and immune function of patients.