姜黄素对代谢综合征的作用机制及临床研究进展

The Impact of Curcumin on Metabolic Syndrome:Mechanism and Clinical Research Advancements

近年来,代谢综合征的患病率不断增加,发病逐渐年轻化。目前代谢综合征患者的管理策略有效性不足,亟需更有效的治疗新方法。大量研究表明姜黄素对代谢综合征具有潜在的治疗作用,姜黄素可通过多种机制在控制肥胖、调节糖脂代谢以及改善胰岛素抵抗等方面起着重要作用。本文总结了姜黄素对代谢综合征的治疗效果及作用机制,以期为姜黄素治疗代谢综合征提供一定的理论依据。

In recent years,the incidence of metabolic syndrome has been increasing,and the age of onset has gradually become younger..The current management strategies for metabolic syndrome,however,are not sufficiently effective,which calls for a novel therapeutic option.Present studies showed that curcumin had potential beneficial effects on metabolic syndrome by alleviating obesity,regulating glucose and lipid metabolism,and decreasing insulin resistance vias various mechanisms.This review summarizes the underlying mechanism and therapeutic benefits of curcumin on metabolic syndrome,to provide some favorable theoretical evidences for its treatment.