植物多糖抗乳腺癌作用的研究进展

Progress on plant polysaccharides against breast cancer

乳腺癌是女性常见的恶性肿瘤之一,其发病率和死亡率呈逐年上升趋势。目前治疗乳腺癌的大多数药物会产生一些不良反应。植物多糖具有多种生物活性,可通过抑制细胞增殖、抑制细胞迁移和侵袭、诱导细胞凋亡、调节细胞周期、抑制肿瘤血管生成、免疫调节、抗氧化等途径抗乳腺癌。综述了植物多糖抗乳腺癌的作用机制研究进展,为植物多糖开发抗乳腺癌新药提供参考。

Breast cancer is one of the most common malignant tumors in women,and its incidence rate and mortality are increasing year by year.At present,most of drugs for breast cancer will produce some adverse reactions.Plant polysaccharides have a variety of biological activities.They have anti-breast cancer effect by inhibiting cell proliferation,inhibiting cell migration and invasion,inducing apoptosis,regulating cell cycle,inhibiting tumor angiogenesis,immune regulation,antioxidant and other ways.This article reviews the research progress on the mechanism of plant polysaccharides against breast cancer,providing reference for the development of plant polysaccharides as new drugs against breast cancer.