盆腔静脉疾病的单中心腔内硬化治疗经验

Endovascular sclerotherapy treatment in pelvic venous disorders:A single-center clinical experience

目的探讨改良腔内硬化栓塞技术治疗盆腔静脉疾病(pelvic venous disorder,PeVD)的安全性和有效性。方法回顾性分析福建医科大学附属第一医院2018年6月至2022年6月采用改良腔内硬化栓塞技术治疗的64例PeVD患者临床资料,比较手术前后的临床症状分级以评估患者症状的改善情况,并参考慢性静脉功能不全问卷(chronic venous insufficiency questionnaire,CIVIQ)评分量表评估本研究量表的可行性。结果技术成功率为100%,患者均未发生弹簧圈异位栓塞。术后1年的临床改善率为100%,临床明显改善率为78.1%,和CIVIQ评分量表具有高度一致性(r=0.797,P<0.001)。术前患者报告结果的平均分为(2.97±0.67)分,术后1年为(0.84±0.62)分,差异有统计学意义(P<0.001)。术前评分越高,完全栓塞率越高(P=0.031),而术后1年的明显改善率越高(P<0.001)。结论改良腔内硬化栓塞技术是治疗PeVD安全有效的方法。

Objective To investigate the safety and efficacy of modified endovascular sclerotherapy treatment in the treatment of pelvic venous disorders(PeVD).Methods The clinical data of 64 patients with PeVD who were treated with modified endovascular sclerotherapy treatment in the First Affiliated Hospital of Fujian Medical University from June 2018 to June 2022 were analyzed retrospectively.The clinical symptom classification before and after surgery was compared to evaluate the improvement of patients'symptoms,and the feasibility of the scale in this study was evaluated by referring to the chronic venous insufficiency questionnaire(CIVIQ)scoring scale.Results The technical success rate was 100%,and no patients had ectopic coil embolization.The clinical improvement rate 1 year after surgery was 100%,and the clinical significant improvement rate was 78.1%,which was highly consistent with the CIVIQ scoring scale(r=0.797,P<0.001).The mean score of patient-reported outcomes before surgery was 2.97±0.67 points,and it was 0.84±0.62 points 1 year after surgery,with a statistically significant difference(P<0.001).The higher the preoperative score,the higher the complete embolization rate(P=0.031),and the higher the significant improvement rate 1 year after surgery(P<0.001).Conclusion Modified endovascular sclerotherapy technique is safe and effective in treating PeVD.