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伴t(10;11)(q22;q23)急性髓系白血病1例并文献复习

Acute myeloid leukemia with t(10;11)(q22;q23):report of 1 case and review of literature
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摘要 目的提高对伴t(10;11)(q22;q23)急性髓系白血病(AML)的认识。方法回顾性分析江苏大学附属人民医院2022年7月收治的1例伴t(10;11)(q22;q23)AML患者的临床资料及诊治经过,并复习相关文献。结果患者,女性,53岁。患者外周血全血细胞减少,骨髓以原始粒细胞为主,易见Auer小体。细胞遗传学常规分析发现46,XX,t(10;11)(q22;q23)[16]/46,XX[4],荧光原位杂交显示MLL基因重排。结论t(10;11)(q22;q23)异常发生率非常低,多见于AML,易合并存在其他染色体异常,伴有这种细胞遗传学异常的AML可能预后不良。
作者 费霞 张凌逸 江云伟 王法春 陈巧云 Fei Xia;Zhang Lingyi;Jiang Yunwei;Wang Fachun;Chen Qiaoyun(Department of Central Laboratory,Affiliated People's Hospital of Jiangsu University,Zhenjiang 212002,China)
出处 《白血病.淋巴瘤》 CAS 2024年第4期242-244,共3页 Journal of Leukemia & Lymphoma
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