某医院高血压患者用药情况调查分析

Investigation and Analysis of Drug Use in Patients with Hypertension in a Hospital

目的:调查某医院高血压患者用药情况及服药依从性,并分析影响服药依从性的因素。方法:选取2021年8月—2023年2月在某医院进行诊治的原发性高血压患者78例进行调查,分析其用药情况,判断服药依从性并进行多因素分析。结果:在78例患者中,使用率最高的药物为苯磺酸氨氯地平片、硝苯地平缓释片,其次为阿利沙坦酯片、马来酸依那普利片,使用率最低的为氯沙坦钾氢氯噻嗪片,涉及的药物类型包括钙离子通道阻滞剂、血管紧张素转换酶抑制剂、血管紧张素Ⅱ受体拮抗剂、复合制剂等。采用联合用药32例,其中二联用药28例,三联用药3例,四联用药1例;使用次数最多为苯磺酸氨氯地平片联合氯沙坦钾片,共有12例,占比15.38%。多因素非条件Logistic回归分析显示,受教育程度、年龄、公费医疗、联合用药、合并疾病、吸烟等都为影响某医院高血压患者服药依从性的重要因素(P<0.05)。结论:某医院高血压患者用药类型多样,多采用联合用药,服药依从性有待提高,受教育程度、年龄、公费医疗、联合用药、合并疾病、吸烟等都为影响某医院高血压患者服药依从性的重要因素。

Objective:To investigate the medication and medication compliance of patients with hypertension in a hospital,and to analyze the factors affecting medication compliance.Methods:From August 2021 to February 2023,78 patients with essential hypertension who were diagnosed and treated in the hospital were investigated,their medication status was analyzed,their medication compliance was judged,and multivariate analysis was performed.Results:Among the 78 patients,the drugs with the highest utilization rate were amlodipine besylate tablets and nifedipine sustained-release tablets,followed by arisartan cilexetil tablets and enalapril maleate tablets,and the lowest utilization rate was losartan potassium hydrochlorothiazide tablets.The types of drugs involved include calcium channel blockers,angiotensin converting enzyme inhibitors,angiotensin II receptor antagonists,compound preparations,etc.There were 32 cases of combined medication,including 28 cases of double medication,3 cases of triple medication and 1 case of quadruple medication.The most frequently used was amlodipine besylate tablets combined with losartan potassium tablets,with a total of 12 cases,accounting for 15.38%.Multivariate unconditional Logistic regression analysis showed that education level,age,public health care,combined medication,combined diseases,smoking and so on were all important factors affecting the medication compliance of patients with hypertension in a hospital(P<0.05).Conclusion:There are various types of medication for patients with hypertension in a hospital,and most of them use combined medication.The medication compliance needs to be improved.Education level,age,free medical care,combined medication,combined disease and smoking are all important factors affecting the medication compliance of patients with hypertension in a hospital.