摘要
钛种植体因具有良好的骨整合能力,在口腔种植手术中得到了广泛的发展和应用。然而,钛种植体的骨整合能力受到表面特性、宿主状态和手术操作等多种因素的影响,可能导致种植体周围炎、无菌性松动等术后并发症。这给口腔种植手术的可靠性和稳定性带来了挑战。为了解决这一问题,目前的主要策略是深入研究骨整合的生物学机制,并开发具有动态响应功能的表面改性方法。因此,本文总结了骨-钛种植体界面的交互作用方式和钛种植体表面改性方法的最新进展,为进一步推动口腔种植手术发展和维护患者身心健康做出展望。
Titanium implants have been widely developed and utilized in oral implant surgery due to their excellent osseointegration capabilities.However,the osseointegration ability of titanium implants is influenced by various factors such as surface properties,host status,and surgical procedures,which may lead to postoperative complications such as peri-implantitis and aseptic loosening.This poses challenges to the reliability and stability of oral implant surgery.To solve this problem,the current main strategy is to deeply investigate the biological mechanisms of osseointegration and develop surface modification methods with dynamic responsive functions.Therefore,this paper summarized the interaction modes between bone and titanium implant interfaces and the latest advances in surface modification methods for titanium implants,providing prospects for further promoting the development of oral implant surgery and maintaining the physical and mental health of patients.
作者
陈天
李歆
刘开政
邓永强
Chen Tian;Li Xin;Liu Kaizheng;Deng Yongqiang(Department of Stomatology,Shenzhen University General Hospital,Shenzhen University,Shenzhen 518055,China;School of Stomatology,Hangzhou Normal University,Hangzhou 311121,China;Institute of Stomatological Research,Shenzhen University,Shenzhen 518055,China;Research Center for Human Tissues and Organs Degeneration,Institute of Biomedicine and Biotechnology,Shenzhen Institute of Advanced Technology,Chinese Academy of Sciences,Shenzhen 518055,China)
出处
《中华口腔医学研究杂志（电子版）》
CAS
2024年第3期200-205,共6页
Chinese Journal of Stomatological Research(Electronic Edition)
基金
国家自然科学基金(青年科学基金,81901058)
深圳市高等院校稳定支持面上项目(20220810163811002)。
关键词
钛种植体
骨整合
骨免疫调节
表面改性
Titanium implants
Osseointegration
Osteoimmunomodulation
Surface modification
