中药穴位贴敷治疗肺胃热盛型小儿支气管肺炎的临床研究

Clinical study on acupoint application of Chinese material medica in the treatment of pediatric bronchopneumonia with exuberant heat of lung and stomach

目的观察中药穴位贴敷联合西医常规治疗肺胃热盛型小儿支气管肺炎的临床疗效。方法选取2021年11月至2022年9月山东第一医科大学附属济南妇幼保健院儿科二病区收治的小儿支气管肺炎属肺胃热盛型患儿100例,随机分为观察组和对照组各50例。对照组使用西医常规治疗,观察组在西医常规治疗的同时联合使用中药穴位贴敷治疗,2组治疗方案均使用至患儿治愈出院。比较2组患儿治疗后住院时间、啰音消失时间、热退时间、咳嗽咳痰消失时间及腹满便秘或便溏酸臭消失时间,观察2组患儿治疗前和治疗第5天中医症候总积分、C反应蛋白(CRP)及降钙素原(PCT),并记录不良反应情况。结果治疗后,2组患儿住院时间、啰音消失时间、热退时间、咳嗽咳痰消失时间、腹满便秘或便溏酸臭消失时间比较,差异均有统计学意义(Z=44.0、281.5、568.5、19.5、0.0,P均<0.05)。治疗5 d后,2组患儿中医症候总积分、CRP、PCT均低于治疗前(Z=-6.205、-6.154、-6.154,P均<0.05),观察组中医症候总积分、CRP、PCT均低于对照组(Z=225.0、702.5、860.5,P均<0.05),2组患儿均无明显不良反应。结论中药穴位贴敷治疗肺胃热盛型小儿支气管肺炎临床疗效显著,值得临床推广。

Objective To observe the clinical efficacy of acupoint application of Chinese material medica in the treatment of pediatric bronchopneumonia with exuberant heat of lung and stomach.Methods A total of 100 children with bronchopneumonia manifested as exuberant heat of lung and stomach were recruited from the second ward of Pediatrics in Jinan Maternal and Child Health Hospital from November 2021 to September 2022,and were randomly divided into an observation group and a control group,with 50 cases in each group.The control group received conventional Western medicine treatment,while the observation group received acupoint application of Chinese material medica together with conventional Western medicine.Both groups were treated until the children were cured and discharged from the hospital.The hospitalization duration,time of rales disappearance,fever regression,cough and phlegm disappearance,abdominal fullness,constipation or loose stool,and sour-smelling stool disappearance of the children in the two groups after treatment were compared.The total score of traditional Chinese medicine(TCM)symptoms,C-reactive(CRP)and procalcitonin(PCT)of the children in the 2 groups were observed before treatment and on the 5th day of treatment,and any adverse reaction was recorded during the trial.Results After the treatment,there were statistically significant differences in hospitalization time,rales disappearance time,fever regression time,cough and phlegm disappearance time,abdominal fullness and constipation or sour-smelling stool disappearance time in the 2 groups(Z=44.0,281.5,568.5,19.5,0.0,all P<0.05).After 5 days of treatment,the overall TCM syndrome score,CRP and PCT levels in both groups decreased compared with the pre-treatment levels(Z=-6.205,-6.154,-6.154,all P<0.05),and the total TCM syndrome score,CRP and PCT in the observation group were lower than those in the control group(Z=225.0,702.5,860.5,all P<0.05).There were no obvious adverse reactions in both groups.Conclusion Acupoint application of Chinese material medica in the treatment of pediatric bronchopneumonia with exuberant heat of lung and stomach has shown remarkable clinical effect and is recommended for clinical promotion.