不同病理类型胃息肉的危险因素分析

Analysis of risk factors of gastricpolyps and their pathological types

目的探讨不同病理类型胃息肉的临床特征及相关资料,分析其发生的危险因素,为胃息肉的预防和诊断提供临床依据。方法选取2021年8月—2022年8月就诊于随州市中心医院消化内科住院接受胃镜检查的患者416例,将胃镜检查确诊为胃息肉并通过病理检验明确病理类型的208例患者作为观察组;同期行胃镜检查结果为慢性胃炎的患者208例作为对照组,收集所有选定的研究对象的相关资料,应用SPSS 26.0统计学软件进行单因素分析,并将有统计学意义的危险因素,进行二元Logistic回归分析,并计算优势比(OR)及95%CI。结果收集病例中增生性息肉(GHp)43例,胃底腺息肉(FGp)149例,炎性息肉(IFp)14例,腺瘤性息肉(GAp)2例。行多因素回归分析发现,幽门螺杆菌(Hp)感染、高脂血症、总胆固醇升高以及载脂蛋白B对于GHP的发生有统计学意义(P<0.05);高脂血症、使用PPIs和PPIs的长期使用以及Hp感染阳性与FGp发生之间的关系具有统计学意义(P<0.05);吸烟史、饮酒史以及Hp感染与IFp发生有统计学意义(P<0.05);高脂血症与GAp的发生具有统计学意义(P<0.05)。结论FGp已成为胃息肉的常见类型,胃息肉的高发年龄段为40~70岁,女性较男性发病率高。GHp、IFp的发生发展与Hp感染呈正相关,FGp与其呈负相关。高脂血症与GHp、FGp及GAp的发生发展有着密切的关系。

Objective To analyse the risk factors of gastric polyps and their pathological patterns by studying the clinical characteristics and related concomitant data of patients with gastric polyps in Suizhou Central Hospital,and provide a clinical basis for the prevention and diagnosis of gastric polyps.Methods Patients admitted to the gastroenterology department of Suizhou Central Hospital from 08/2021 to 08/2022 were selected.SPSS 26.0 statistical software was applied for statistical analysis and data processing.Results A total of 416 cases were collected,including 43 hyperplastic polyps,149 fundic gland polyps,14 inflammatory polyps and 2 adenomatous polyps.A multifactorial regression analysis revealed that Hp infection,hyperlipidaemia,elevated total cholesterol and Apo B were statistically significant for the development of hyperplastic polyps.Hyperlipidaemia,use of PPI and prolonged use of PPI and positive Hp infection were statistically significant in relation to the development of fundic polyps.History of smoking,alcohol consumption and Hp infection were statistically significant with the occurrence of gastric inflammatory polyps.Hyperlipidaemia was statistically associated with the occurrence of adenomatous polyps.Conclusion Gastric fundic polyps have become a common type of gastric polyp.The high incidence of gastric polyps is from the ages of 40 to 70,with a higher incidence in women than in men.The development of hyperplastic and inflammatory gastric polyps is positively associated with Hp infection,while fundic polyps are negatively associated with them.Hyperlipidaemia is strongly associated with the development of hyperplastic polyps,fundic gland polyps and adenomatous polyps.