麻醉药物对术后睡眠障碍影响的研究进展

Research advances on the effects of anesthetic drugs on postoperative sleep disorders

保持人体生理和心理功能的正常运作,需要遵循规律的睡眠模式和周期,而围手术期出现的睡眠障碍近年来关注度也不断提升。全身麻醉会改变睡眠结构,导致睡眠障碍,继而可能会引起患者痛觉过敏、术后恢复不良等情况。越来越多的证据表明,围手术期的多种因素与术后的睡眠障碍相关,全麻药物作为一个独立危险因素可能导致全身麻醉后的睡眠障碍。文章主要以临床实验和基础实验,就不同的麻醉药物对患者术后睡眠阶段及睡眠质量的影响进行综述。

Normal sleep patterns and sleep cycles are crucial for maintaining the proper functioning of physiological and psychological processes in the human body.In recent years,there has been a growing focus on sleep disorders that arise during the perioperative period.General anesthesia can alter sleep structure,leading to sleep disorders,which may result in patient hyperalgesia and poor postoperative recovery.Increasing evidence suggests that various factors during the perioperative period are associated with postoperative sleep disorders,and general anesthetic drugs,as an independent risk factor,may contribute to sleep disorders following general anesthesia.This article primarily reviews the effects of different anesthetic drugs on patients’postoperative sleep stages and sleep quality based on clinical experiments and laboratory experiments.