耳甲电针对新型冠状病毒感染后睡眠障碍患者大脑皮质兴奋性的调节作用

Regulation of Electroacupuncture of Auricular Concha on Excitability of Cerebral Cortex in Patients with Sleep Disorder after Novel Coronavirus Infection

目的:探讨耳甲电针对新型冠状病毒感染后睡眠障碍患者大脑皮质兴奋性的调节作用。方法:选取2022年6月至2023年6月广东省佛山市第八人民医院金沙分院中医科和康复科门诊失眠患者和健康志愿者各20例作为研究对象,采用匹兹堡睡眠质量指数(PSQI)量表和过度觉醒量表(HAS)来评估受试者的一般情况,同时利用单脉冲经颅磁刺激技术,采集2组受试者经耳甲电针治疗前后的皮层运动诱发电位相关指标,观察耳甲电针对皮层运动诱发电位潜伏期和波幅的调节作用。结果:治疗前观察组与对照组比较,患者的皮层运动诱发电位潜伏期短,波幅大;治疗后,患者的皮层运动诱发电位潜伏期未见显著变化,但波幅有所下降。结论:耳甲电针可以通过激活自主神经系统,调节大脑皮质兴奋性,从而抑制新型冠状病毒感染后睡眠障碍患者大脑皮质过度觉醒状态,可能是耳甲电针治疗失眠的机制之一。

Objective:To investigate the regulatory effect of auricular electroacupuncture on cortical excitability in patients with sleep disorder after novel coronavirus infection.Methods:A total of 20 patients with insomnia and 20 healthy volunteers were included in the study from June 2022 to June 2023,admitted to the Traditional Chinese Medicine Department and Rehabilitation Clinic of the Eighth People′s Hospital of Foshan City,Guangdong Province.Pittsburgh Sleep Quality Index(PSQI)and Hyperarousal Scale(HAS)were used to evaluate the general condition of the subjects.Meanwhile,single transcranial magnetic stimulation was used to collect the cortical motor evoked potential related indicators before and after auricular electroacupuncture in the two groups to observe the regulation effect of auricular electroacupuncture on the latency and amplitude of cortical motor evoked potential.Results:Before treatment,the latent period of cortical motor evoked potential was short and the amplitude was large in patients.After treatment,the latent period of cortical motor evoked potential did not change significantly,but its amplitude decreased in patients.Conclusion:Auricular electroacupuncture can regulate cortical excitability by activating autonomic nervous system,so as to inhibit excessive cortical arousal in patients with sleep disorder after novel coronavirus infection,which may be one of the mechanisms of auricular electroacupuncture in the treatment of insomnia.